YRC Public Data Repository - Protein Structure Prediction

Protein:	pex13
Organism:	Schizosaccharomyces pombe
Length:	288 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pex13.

Description	E-value	Query Range	Subject Range
gi\|207342984 - gi\|207342984\|gb\|EDZ70588.1\| YLR191Wp-like protein [Saccharomyces cerevisiae AWRI1631] PEX13_YEAST - Peroxisomal membrane protein PAS20 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PEX13... PEX13 - Integral peroxisomal membrane required for the translocation of peroxisomal matrix proteins, interac...	223.0	[0..6]	[288..66]
gi\|119195595, gi... - gi\|90307187\|gb\|EAS36818.1\| hypothetical protein CIMG_02172 [Coccidioides immitis RS], gi\|119195595\|r...	213.0	[0..67]	[288..24]
gi\|26327789 - gi\|26327789\|dbj\|BAC27635.1\| unnamed protein product [Mus musculus]	212.0	[0..9]	[288..54]
gi\|114577535 - gi\|114577535\|ref\|XP_525763.2\| PREDICTED: peroxisome biogenesis factor 13 [Pan troglodytes] PEX13 - peroxisomal biogenesis factor 13	211.0	[0..9]	[288..52]
gi\|6682845 - gi\|6682845\|dbj\|BAA88906.1\| PEX13 [Cricetulus griseus]	210.0	[0..9]	[288..54]
gi\|109501111, gi... - ref\|XP_223684.2\| similar to Peroxisomal membrane protein PEX13 (Peroxin-13) [Rattus norvegicus], gi\|...	210.0	[0..9]	[288..52]
gi\|49087424, gi\|... - gi\|67522108\|ref\|XP_659115.1\| hypothetical protein AN1511.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	209.0	[0..64]	[288..135]
gi\|42545553, gi\|... - gi\|46107566\|ref\|XP_380842.1\| hypothetical protein FG00666.1 [Gibberella zeae PH-1], gi\|42545553\|gb\|E...	209.0	[0..67]	[288..213]

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Predicted Domain #1

Region A:
Residues: [1-102]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METNQNEKGP SLPSYPAGGI MSVSNSNADT NQGVTQHPLA NRIVNPNYYN MGFNPYSGFN  60
   61 SFIPSFNPFV PLETNLPGNG PISSLQVIES IVGAVGSIAQ VL

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [103-193]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESTLMAAHMS YNTFVSVSEN LNKLKSSIGA IFGIVSLLSR LKRLVLKFFK HSKIDEMNSQ  60
   61 EYDVFEKEEG NHKNSIYSIV SSLAIILGLV G

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	13.0
Match:	1zwwA
Description:	Crystal structure of endophilin-A1 BAR domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [194-288]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPYAIIRLFK NIYEKEKQIQ QAKIRKKIDS LEFCKADYEF MSRDPGVEMS LKKGDIIAIL  60
   61 SKTDTQGNPC EWWQGRKRSG ETGWFPSNYC SIISR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	21.0
Match:	1jqqA
Description:	Peroxisomal membrane protein Pex13p
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	2.49184519104882	bayes_pls_golite062009
protein binding	2.29371158534719	bayes_pls_golite062009
cytoskeletal protein binding	1.67112127425228	bayes_pls_golite062009
transporter activity	1.30447542854757	bayes_pls_golite062009
transmembrane transporter activity	1.08558010881058	bayes_pls_golite062009
actin binding	0.75525840382431	bayes_pls_golite062009
substrate-specific transporter activity	0.566172161499832	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.325817349097199	bayes_pls_golite062009
ion transmembrane transporter activity	0.00508584255499911	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: