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View Structure Prediction Details

Protein: SPAC22H12.05c
Organism: Schizosaccharomyces pombe
Length: 728 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC22H12.05c.

Description E-value Query
Range
Subject
Range
gi|62897225 - gi|62897225|dbj|BAD96553.1| transforming growth factor, beta-induced, 68kDa variant [Homo sapiens]
433.0 [0..24] [614..98]
BGH3_MOUSE - Transforming growth factor-beta-induced protein ig-h3 OS=Mus musculus GN=Tgfbi PE=1 SV=1
433.0 [0..24] [614..98]
gi|109078702 - gi|109078702|ref|XP_001111447.1| PREDICTED: transforming growth factor, beta-induced, 68kDa isoform ...
432.0 [0..24] [614..98]
gi|76623057 - gi|76623057|ref|XP_588272.2| PREDICTED: similar to Transforming growth factor-beta induced protein I...
432.0 [0..24] [614..159]
gi|114601808 - gi|114601808|ref|XP_001169033.1| PREDICTED: transforming growth factor, beta-induced, 68kDa isoform ...
430.0 [0..24] [614..56]
gi|2116676 - gi|2116676|dbj|BAA20089.1| RGD-containing collagen associated protein [Porcine rotavirus]
BGH3_PIG - Transforming growth factor-beta-induced protein ig-h3 OS=Sus scrofa GN=TGFBI PE=1 SV=1
428.0 [0..24] [614..98]
gi|73971374 - gi|73971374|ref|XP_538640.2| PREDICTED: similar to Transforming growth factor-beta induced protein I...
425.0 [0..24] [614..76]

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Predicted Domain #1
Region A:
Residues: [1-152]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNLQFRLYLL FILLFISFAN GKNEYEDKST SIIDLLSSKS QFSKLIRRLQ RNRLVPYLNR  60
   61 NKGLTLFAPL NEAFPDDSIE PNLLYYIVNT TELDRSVLRT QLKSSDGQQI ALKIHYKAET 120
  121 GRAYDKVNNA QIVQSNWRAD SGVVQVIDNI ID

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 5.36
Match: 1x3bA
Description: Solution structure of the FAS1 domain of human transforming growth factor-beta induced protein IG-H3
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [153-290]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPPPALEILS SEKDFSIFHR LSVAWVGEYS SVTMLVPDSS AFLNVYTNTE LAYLYSMYAA  60
   61 EDVKTLIHQH ILVNQRVYAE DVIEPKTFHY KNGISISMKF DKDQKKLFIN DVSTTKYDLL 120
  121 TFSGAIHTVS SLINPEII

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.154902
Match: 1w7dA
Description: No description for 1w7dA was found.

Predicted Domain #3
Region A:
Residues: [291-559]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SFTPAKYLIG IGAAWFSEKL SRERKSISVD KTSKRAILAP TNWAYREIID IDYHIIENFD  60
   61 LPAPNKYALY VTNIKSGNSV GEDTNALVRI ATGSAGEMYV NVETRSIQSE NIGNVSLYVL 120
  121 DKDIEPPQPL LSQLILVDEI SFSVRYLASL GLGDYTKVTW FLVKNSAWTQ LGLVHLVLQQ 180
  181 NLELLESVML DYAFEGIAFY GSSDEAWASG NYTTLSNKEF LIEGVYEDSN SRNKRDLLRI 240
  241 NNEIYEVQTR DLLVKDGVVH LVDKVKLPF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 31.154902
Match: 1o70A
Description: Fasciclin I
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [560-728]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SVSQKDMIIA GGRKEFLELL DKFEMLDMLD SGYPVVVPSL TGSDVNTKDS SFAERHIIDP  60
   61 EKRNFVISGS RLSVDSSPWI SIQDYGYSEL GNVYFVQNAI PTKRQNRWRI TFISISGLLL 120
  121 SVGICVLCYK IYFKFFRNRF MNQGEREPLL APADSDTMAG RRNSSSLSV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle