YRC Public Data Repository - Protein Structure Prediction

Protein:	efc25
Organism:	Schizosaccharomyces pombe
Length:	987 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for efc25.

Description	E-value	Query Range	Subject Range
gi\|38101805, gi\|... - gi\|39974965\|ref\|XP_368873.1\| hypothetical protein MG00371.4 [Magnaporthe grisea 70-15], gb\|EAA48713....	608.0	[0..277]	[986..411]
gi\|85083539 - gi\|85083539\|ref\|XP_957140.1\| hypothetical protein [Neurospora crassa OR74A] gi\|32411749, gi\|... - gi\|32411749\|ref\|XP_326355.1\| hypothetical protein [Neurospora crassa], gi\|28918226\|gb\|EAA27904.1\| hy...	605.0	[0..277]	[986..418]
gi\|46122041, gi\|... - gi\|46122041\|ref\|XP_385574.1\| hypothetical protein FG05398.1 [Gibberella zeae PH-1], gi\|42550830\|gb\|E...	603.0	[0..277]	[986..417]
gi\|67523347, gi\|... - gi\|67523347\|ref\|XP_659734.1\| hypothetical protein AN2130.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	578.0	[0..276]	[986..443]
gi\|116208070, gi... - gi\|88183925\|gb\|EAQ91393.1\| hypothetical protein CHGG_03328 [Chaetomium globosum CBS 148.51], gi\|1162...	576.0	[0..277]	[986..348]
gi\|114195584, gi... - gi\|115387989\|ref\|XP_001211500.1\| conserved hypothetical protein [Aspergillus terreus NIH2624], gi\|11...	536.0	[0..277]	[986..441]
gi\|169775981 - gi\|169775981\|ref\|XP_001822457.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|83771192 - gi\|83771192\|dbj\|BAE61324.1\| unnamed protein product [Aspergillus oryzae]	528.0	[0..277]	[986..447]
gi\|66853598, gi\|... - gi\|71002558\|ref\|XP_755960.1\| cell division control protein Cdc25 [Aspergillus fumigatus Af293], gi\|6...	524.0	[0..276]	[986..444]
gi\|111061527 - gi\|111061527\|gb\|EAT82647.1\| hypothetical protein SNOG_10312 [Phaeosphaeria nodorum SN15]	505.0	[0..277]	[986..365]
gi\|119175274, gi... - gi\|90298683\|gb\|EAS28314.1\| hypothetical protein CIMG_09518 [Coccidioides immitis RS], gi\|119175274\|r...	491.0	[0..277]	[986..386]

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Predicted Domain #1

Region A:
Residues: [1-146]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRRPNLDRLR LKSRQGFETS VSKPSTPSYS TYSLSPTFSD KSVLSPSTMS DSYALSSTYT  60
   61 AGSSYQNGES DYFGSLPTPS SDKSSTSPFP YLKGSFDDRF SSTHSLTRQP SPRSPLTPLK 120
  121 GNTRASPEIR YVSDFTPPSS PFEDMQ

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [147-331]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASVHSLPLSG CSIGPVRTNH SSSLSNSSNS LLQTESSLRP NSSFVNSPFF PLPSSDDLFL  60
   61 NDRVINLFLF YEKFSYLFTH LLSAIKSRDA LSIPSLVLSL QEELFNLCQQ TGTFYLLQHN 120
  121 LLQNFEFENP IKLHFDKIIP YFSRLTVLTF SNRAFIFPDH TFPRLQQSAE DFLYHLQFFF 180
  181 TLCAN

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [332-415]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSLYLSRFCY YPSFVPNTPF GGKWTNNGLS AVSSAYRTRL LEPCLPELDK CVWFLLKNCD  60
   61 EFIENFSDFA DEEYVFEICS TITS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [416-987]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HSEQIFNKLE SWDMSIYFDK DLSECEQATN FAVQSYFVTK QRCYDLLTDL VCSSQDLMME  60
   61 HSNDFSTMPT MIASIAVAFQ TLFENVCDFL KVRAALVDEM QELATKEFEN KFSNANTAKD 120
  121 DEPARQTNKG TTRISRSSDF TAVSEMSKDT LTLGRNSLQS ILMLDNLLTN KVVQSDNNVK 180
  181 GGTLPALVHY LVQNVHLNKD FRHSFLLTYK TFTTPQELFT LLVILFHELP PPGLDATAYS 240
  241 SWEKGDNFVT KKNVCTVMNL WVQKYFFEDL KARNTLYLIS EMRTFLRDHV VPSFHIGSVI 300
  301 LSEIDNLWTE EPPDSLTQRL LSSPMATFIS LNVYAYTPEE FASQMTLLEF DYLKQIPSRE 360
  361 WIFRSWVSRD SRSAVRNYIN FSNCFTYWII NCILEKKNTK ARTAVISFFI QTAYKCLSLQ 420
  421 NFSTLMSIVS ALNSAPIYRL HAAYKLVKAE DIICLSGLRE IVETKKNFST YRALLRKAEL 480
  481 PCVPFLGVIL SDLTFIDEGN PDVLDSSPHL LSFNKRHRLA DVVADVCRFQ SSSYEMQSNT 540
  541 DLQSYILHRC RFVNQDLSYL FDKSLSLEPR SS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	127.0
Match:	1xd4A
Description:	Crystal structure of the DH-PH-cat module of Son of Sevenless (SOS)
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits