YRC Public Data Repository - Protein Structure Prediction

Protein:	mrpl8
Organism:	Schizosaccharomyces pombe
Length:	207 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mrpl8.

Description	E-value	Query Range	Subject Range
gi\|11544674, gi\|... - gi\|32412071\|ref\|XP_326516.1\| hypothetical protein ( mitochondrial ribosomal protein YmL8 homolog [im... gi\|85103976 - gi\|85103976\|ref\|XP_961635.1\| mitochondrial ribosomal protein YmL8 [Neurospora crassa OR74A] )	224.0	[0..6]	[193..7]
gi\|49086978, gi\|... - gi\|67521782\|ref\|XP_658952.1\| hypothetical protein AN1348.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	222.0	[0..6]	[190..7]
gi\|39970085, gi\|... - gi\|39970085\|ref\|XP_366433.1\| hypothetical protein MGG_10651 [Magnaporthe grisea 70-15], gb\|EAA46865....	218.0	[0..6]	[205..7]
gi\|66849943, gi\|... - gi\|70995084\|ref\|XP_752308.1\| 50S ribosomal protein L17 [Aspergillus fumigatus Af293], gi\|66849943\|gb... gi\|159131064 - gi\|159131064\|gb\|EDP56177.1\| 50S ribosomal protein L17 [Aspergillus fumigatus A1163]	216.0	[0..6]	[193..7]
gi\|68487502, gi\|... - gi\|68487575\|ref\|XP_712336.1\| likely mitochondrial ribosomal protein L8 (E. coli L17) [Candida albica... gi\|238880150 - gi\|238880150\|gb\|EEQ43788.1\| hypothetical protein CAWG_02037 [Candida albicans WO-1] orf19.6129, orf1... - orf19.6129 CGDID:CAL0005986 Assembly 19, Contig19-10238 (20539, 21306) CDS, translated using codon t...	212.0	[0..1]	[205..1]
gi\|46137123, gi\|... - gi\|46137123\|ref\|XP_390253.1\| hypothetical protein FG10077.1 [Gibberella zeae PH-1], gi\|42547550\|gb\|E...	207.0	[0..6]	[191..7]
MRPL8 - Mitochondrial ribosomal protein of the large subunit RM08_YEAST - 54S ribosomal protein L8, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=...	207.0	[0..8]	[190..7]
gi\|88184961, gi\|... - gi\|88184961\|gb\|EAQ92429.1\| hypothetical protein CHGG_00664 [Chaetomium globosum CBS 148.51], gi\|1161...	205.0	[0..6]	[178..7]
gi\|220698584, gi... - gi\|238489917\|ref\|XP_002376196.1\| 50S ribosomal protein L17 [Aspergillus flavus NRRL3357], gi\|2206985... gi\|169763942 - gi\|169763942\|ref\|XP_001727871.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|83770899 - gi\|83770899\|dbj\|BAE61032.1\| unnamed protein product [Aspergillus oryzae]	204.0	[0..6]	[197..7]

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Predicted Domain #1

Region A:
Residues: [1-119]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTKTLYYRKL GRTSAHRQAL LRNLVTSLVK HESIQTTWAK AKEAQRFAEK LITMAKRANP  60
   61 QNNRKGLAEG MVFEKETTLK KVFDVLVPRY NGRRCGYTRL LKLPPRSTDN APMGVLEFV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	47.0
Match:	1p85L
Description:	70S ribosome functional complex
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [120-207]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGPKDIRFHM TAKTVGICLA QQKALTPITR KNIHKVLLFR KNGKAEFDQL VQKEKESEHA  60
   61 RLKEDHEDEK TVKKDWKRGD PIPRPTYI

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.671	a.60.6	DNA polymerase beta, N-terminal domain-like
View	Download	0.573	a.133.1	Phospholipase A2, PLA2
View	Download	0.571	a.60.6	DNA polymerase beta, N-terminal domain-like
View	Download	0.560	a.24.13	Domain of the SRP/SRP receptor G-proteins
View	Download	0.551	a.29.14	Description not found.
View	Download	0.544	a.7.6	Ribosomal protein S20
View	Download	0.531	a.133.1	Phospholipase A2, PLA2
View	Download	0.530	a.4.5	"Winged helix" DNA-binding domain
View	Download	0.498	a.4.1	Homeodomain-like
View	Download	0.454	a.133.1	Phospholipase A2, PLA2

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits