YRC Public Data Repository - Protein Structure Prediction

Protein:	SPBC18E5.10
Organism:	Schizosaccharomyces pombe
Length:	452 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC18E5.10.

Description	E-value	Query Range	Subject Range
gi\|71004398, gi\|... - gi\|71004398\|ref\|XP_756865.1\| hypothetical protein UM00718.1 [Ustilago maydis 521], ref\|XP_398333.1\| ...	642.0	[0..4]	[451..363]
gi\|111661793 - gi\|111661793\|gb\|ABH12158.1\| mitochondrial complex I subunit NDUFV1 [Gorilla gorilla] NDUV1_GORGO - NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Gorilla gorilla gorilla GN=NDUFV1 P...	631.0	[0..1]	[450..7]
gi\|50258845, gi\|... - gi\|50258845\|gb\|EAL21530.1\| hypothetical protein CNBD2240 [Cryptococcus neoformans var. neoformans B-...	629.0	[0..3]	[449..50]
NDUV1_PANTR - NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Pan troglodytes GN=NDUFV1 PE=2 SV=1	629.0	[0..1]	[450..7]
gi\|124000113, gi... - gi\|124000113\|gb\|ABM87565.1\| NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [synthetic constru... NDUFV1 - NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa	628.0	[0..1]	[450..7]
gi\|58265992, gi\|... - gi\|58265992\|ref\|XP_570152.1\| NADH-ubiquinone oxidoreductase 51 kDa subunit [Cryptococcus neoformans ...	628.0	[0..3]	[449..50]
gi\|66805535, gi\|... - gi\|66805535\|ref\|XP_636489.1\| ubiquinone oxidoreductase [Dictyostelium discoideum AX4], gi\|60464845\|g... NDUV1_DICDI - NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Dictyostelium discoideum GN=ndufv1 ...	627.0	[0..2]	[450..25]
NDUV1_PONPY - NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Pongo pygmaeus GN=NDUFV1 PE=2 SV=1 NDUV1_PONAB - NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Pongo abelii GN=NDUFV1 PE=2 SV=1	627.0	[0..1]	[450..7]
NDUV1_BOVIN - NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Bos taurus GN=NDUFV1 PE=1 SV=2	627.0	[0..1]	[449..7]
gi\|73982783 - gi\|73982783\|ref\|XP_851761.1\| PREDICTED: similar to NADH dehydrogenase (ubiquinone) flavoprotein 1, 5...	627.0	[0..1]	[450..7]

Back

Predicted Domain #1

Region A:
Residues: [1-452]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSRGHCCKL KHSFNGLRNV ALKRLVGSKA GYRMFPNLIE KRIRRIDDAL ADGEYENLSE  60
   61 ILKYDPLNII ELVQESELRG RGRYGFPTGE KMLSLYKATS SERGRKEKPV VIVNAAENDI 120
  121 GSFKDRLLLR HEPHKIIEGA IIAARAVEAS ACYLFIRKDY YEETVMMQKC IIQAYAKKLL 180
  181 GKNLLGTSIG LELLIHPGAG SYITGEESAL IQSLQGEFPV PDIPINNTIT SGLFGLPTLV 240
  241 LNVETVSNLP AIIKKGPKFF ISMGRPNNRG TKLFSISGEV NEPNVIEACM SIPLKDLIEN 300
  301 YAGGVRGGWN KLVGIFPGGP CSGILNKNQC EQVTMDFDSL KALDSSLGTG SVIVLNDHDQ 360
  361 IFESLLNFAK FYSTNTCHTC PVCRDGVEDV IETLKGLKDG HAHLSQLKDM FSKFNMPSSS 420
  421 KVFCGFGDSM RHQIHSIQRN FPDQITFRTK VT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	151.0
Match:	2fug1
Description:	Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
NADH dehydrogenase activity	13.4136491947011	bayes_pls_golite062009
NADH dehydrogenase (ubiquinone) activity	12.443012098477	bayes_pls_golite062009
NADH dehydrogenase (quinone) activity	12.1743193111446	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor	11.5132141901667	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	10.8948060301507	bayes_pls_golite062009
oxidoreductase activity	6.75377893144873	bayes_pls_golite062009
4 iron, 4 sulfur cluster binding	5.81993873720697	bayes_pls_golite062009
formate dehydrogenase activity	5.21374407932502	bayes_pls_golite062009
iron-sulfur cluster binding	4.82023808325158	bayes_pls_golite062009
metal cluster binding	4.82023808325158	bayes_pls_golite062009
electron carrier activity	1.50427278540084	bayes_pls_golite062009
catalytic activity	1.46362311772849	bayes_pls_golite062009
binding	1.25265721111105	bayes_pls_golite062009
oxidoreductase activity, acting on hydrogen as donor	0.530794334701446	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	0.471058486160512	bayes_pls_golite062009
ferredoxin hydrogenase activity	0.281674499766589	bayes_pls_golite062009
oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor	0.281674499766589	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: