YRC Public Data Repository - Protein Structure Prediction

Protein:	mug184
Organism:	Schizosaccharomyces pombe
Length:	551 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mug184.

Description	E-value	Query Range	Subject Range
gi\|2288929\|emb\|C... - IgA1 protease [Streptococcus oralis] gi\|2288929 - gi\|2288929\|emb\|CAA73666.1\| IgA1 protease [Streptococcus oralis]	163.0	[0..206]	[517..340]
gi\|31544538, gi\|... - gi\|31544538\|ref\|NP_853116.1\| hypothetical protein MGA_1228 [Mycoplasma gallisepticum R], gi\|31541383...	163.0	[0..10]	[535..11]
IGA1B_STREE - Immunoglobulin A1 protease OS=Streptococcus pneumoniae GN=iga PE=3 SV=1	161.0	[0..209]	[517..408]
gi\|12642614 - gi\|12642614\|gb\|AAK00311.1\|AF315821_1 DNA-dependent RNA polymerase II largest subunit RPB1 [Monosiga ...	142.0	[0..221]	[460..1460]
gi\|3511287, gi\|7... - pir\|\|T31670 DNA-directed RNA polymerase (EC 2.7.7.6) II largest chain - Mastigamoeba invertens (frag...	137.0	[0..198]	[478..1410]
gi\|124530383, gi... - gi\|124530383\|ref\|ZP_01701069.1\| chaperone protein DnaJ [Escherichia coli B], gi\|124499274\|gb\|EAY4676... gi\|110640228, gi... - gi\|110640228\|ref\|YP_667956.1\| chaperone protein DnaJ [Escherichia coli 536], gi\|110341820\|gb\|ABG6805...	134.0	[0..6]	[220..9]
PK1L3_MOUSE - Polycystic kidney disease protein 1-like 3 OS=Mus musculus GN=Pkd1l3 PE=2 SV=1	132.0	[0..190]	[503..297]
DNAJ_BORBR - Chaperone protein DnaJ OS=Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50) GN=dna... DNAJ_BORBR - Chaperone protein DnaJ OS=Bordetella bronchiseptica GN=dnaJ PE=3 SV=1	125.0	[0..9]	[206..2]
DNAJ_METCA - Chaperone protein DnaJ OS=Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath) GN=dnaJ ... DNAJ_METCA - Chaperone protein dnaJ OS=Methylococcus capsulatus GN=dnaJ PE=3 SV=1	123.0	[0..9]	[234..2]

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Predicted Domain #1

Region A:
Residues: [1-128]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLARPETDTS VDYYAILKLQ KNATFQQIRK QYLFLALQYH PDRNPGDEER AVKRFQRLQL  60
   61 AHEVLSDATK RLIYDQLFGL STRTRSQYKP NSTSNPSKHT SAYASYNKGK NSKWSSPFAS 120
  121 TTKKPQES

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	22.30103
Match:	1xblA
Description:	NMR STRUCTURE OF THE J-DOMAIN (RESIDUES 2-76) IN THE ESCHERICHIA COLI N-TERMINAL FRAGMENT (RESIDUES 2-108) OF THE MOLECULAR CHAPERONE DNAJ, 20 STRUCTURES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.76528619532104	bayes_pls_golite062009
protein binding	1.63230390088325	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [129-263]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SEKYSKKSST RKKEHFNKKP SFPRDTEYSH IYNMKYDPRS GIGIRVKRQE PESLKKENNN  60
   61 SDYLPKSAMK QKKGGPKDSS KHPSNDGKIP ESKPSVYKSR ASNLFSSNEQ SIHSSFGSKF 120
  121 HFDKSSNPFS FEFSP

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [264-462]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSNAAKPSNS EECNIPKFNS SFKTSNDFFT FTKTEESSPY SFSFKLEDSN TPKFKSSSKP  60
   61 VKSSFVFTKP EAESSNPFSF DFGSSGPKSR SDTRNNIRTP LWTSSVFEKP ESDLPNKTAF 120
  121 GFMRSNTSTF NQKCDDFSSA SFMKEKTEFE EQLQEDNDHS LGDLFSKINI STESPSVAMP 180
  181 SIPVIQPPSF PIFSSIDFN

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [463-551]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VRNREYWNQL MVFQKLYSKY CTESQHFINS WINIKKELHI VPVNWEIFEK VEKSWDQCEE  60
   61 FVAEFRQTEE KYFLFLKRLR ELINKNQML

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.912	a.23.1	HSC20 (HSCB), C-terminal oligomerisation domain

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: