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View Structure Prediction Details

Protein: SPBC1711.08
Organism: Schizosaccharomyces pombe
Length: 336 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC1711.08.

Description E-value Query
Range
Subject
Range
gi|73963740 - gi|73963740|ref|XP_537523.2| PREDICTED: similar to Activator of 90 kDa heat shock protein ATPase hom...
373.0 [0..2] [336..16]
AHSA1 - AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
373.0 [0..2] [336..16]
gi|114654169, gi... - gi|114654173|ref|XP_001165345.1| PREDICTED: hypothetical protein isoform 4 [Pan troglodytes], gi|114...
372.0 [0..2] [336..16]
gi|74177617 - gi|74177617|dbj|BAE38913.1| unnamed protein product [Mus musculus]
372.0 [0..2] [336..16]
gi|109084442 - gi|109084442|ref|XP_001103794.1| PREDICTED: AHA1, activator of heat shock 90kDa protein ATPase homol...
371.0 [0..2] [336..16]
gi|55730658 - gi|55730658|emb|CAH92050.1| hypothetical protein [Pongo abelii]
gi|197100599 - gi|197100599|ref|NP_001127499.1| activator of heat shock 90kDa protein ATPase homolog 1 [Pongo abeli...
371.0 [0..2] [336..16]
gi|109479740, gi... - gi|169234816|ref|NP_001108506.1| hypothetical protein LOC681996 [Rattus norvegicus], gi|165970860|gb...
370.0 [0..2] [336..16]

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Predicted Domain #1
Region A:
Residues: [1-201]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSATSINPNN WHWTSKDCRV WSHEYFNKEL PKIQASEGPT SARITQVNSC EGDVDVSMRK  60
   61 RKVITIFDLK IQMEFKGETK DGVEATGSIT CPELSYDLGY SDYVFDIDIY SASKEKEPIK 120
  121 ELVREKIIPQ IRQLFSGFSQ VLLQTHGDDV YLSTEEHNGN AARGLPVHSS FKQNNSSQTS 180
  181 SNKGTTTVAA GSGSDGSRVS A

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 50.045757
Match: 1usvB
Description: The Structure of the complex between Aha1 and HSP90
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
chaperone binding 2.87169826684641 bayes_pls_golite062009
ATPase regulator activity 2.31076586548557 bayes_pls_golite062009
binding 2.05200237600398 bayes_pls_golite062009
ATPase activator activity 1.99816875782377 bayes_pls_golite062009
protein binding 1.12549021331477 bayes_pls_golite062009
heat shock protein binding 0.87871487226722 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [202-336]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VVNTADISEN YTFDAPANEL YATFLDPARV AAWSRAPPQL DVRPQGAFSL FHGNVVGKFL  60
   61 VLEENKKIVQ TWRLSSWPTG HYAEITFTFD QADSYTTLRM IMKGVPIGEE EVVQGNIQDY 120
  121 YIRPIKTVFG FGAVL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.09691
Match: 1x53A
Description: The solution structure of the C-terminal domain of human Activator of 90 kDa heat shock protein ATPase homolog 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.44038379867996 bayes_pls_golite062009
hydrolase activity 0.271155119882887 bayes_pls_golite062009
protein binding 0.186935278553638 bayes_pls_golite062009
catalytic activity 0.0116392906163881 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle