YRC Public Data Repository - Protein Structure Prediction

Protein:	SPCC1235.03
Organism:	Schizosaccharomyces pombe
Length:	399 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPCC1235.03.

Description	E-value	Query Range	Subject Range
gi\|162317816, gi... - gi\|162318428\|gb\|AAI57130.1\| NEDD4 binding protein 2 [synthetic construct], gi\|162317816\|gb\|AAI56352.... gi\|67906816 - gi\|67906816\|ref\|NP_001020088.1\| Nedd4 binding protein 2 [Mus musculus]	337.0	[0..6]	[389..1333]
N4BP2 - NEDD4 binding protein 2	334.0	[0..6]	[389..1421]
gi\|109074047 - gi\|109074047\|ref\|XP_001093946.1\| PREDICTED: similar to Nedd4 binding protein 2 isoform 2 [Macaca mul...	334.0	[0..6]	[389..1421]
gi\|114593666 - gi\|114593666\|ref\|XP_526557.2\| PREDICTED: Nedd4 binding protein 2 isoform 2 [Pan troglodytes]	331.0	[0..6]	[389..1421]
gi\|73951873 - gi\|73951873\|ref\|XP_536248.2\| PREDICTED: similar to Nedd4 binding protein 2 [Canis familiaris]	325.0	[0..6]	[389..1423]
gi\|109499684, gi... - gi\|109500601\|ref\|XP_001077973.1\| PREDICTED: similar to Nedd4 binding protein 2 [Rattus norvegicus], ...	324.0	[0..6]	[376..1413]

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Predicted Domain #1

Region A:
Residues: [1-305]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFSDLSAARV QLVQAKCQND LVRSSDELLN HRAIQESEQI ETAADALITS NIGHRSRQRK  60
   61 KKTKKATNSR KPLSKFQSNT EEVNEDPILK PSLSVWENNR LLIEKLTSIL NIPSSQINHE 120
  121 FYKNSSAWPI TIRNLIHRHQ PLSNITNNEL MKYQEEATQL AKDTGLSLKI CTDVLICSND 180
  181 YKNALWILCL IKETQHNEMG NIKLSSQTAK SNSSTQTKTC LNDQSSKLVE DDEALSAEDC 240
  241 NRLAEEYLEL RNMQYSNSAK EYRRSKSNHL FGGSAMYHAQ LGREYHEKAL KYRSLAMRSL 300
  301 AHSGT

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [306-399]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SHSLDLHGAT VREAKTIVRE RVAAWWAKEA DTSPNSIRPF VIVTGRGNHS IGLEARLLPA  60
   61 IVRLLQQDHW RFDAEHGQIT VYGINRHSKL NSNA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	22.0
Match:	2d9iA
Description:	No description for 2d9iA was found.

Predicted functions:

Term	Confidence	Notes
ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity	1.739613580002	bayes_pls_golite062009
polynucleotide kinase activity	1.739613580002	bayes_pls_golite062009
polydeoxyribonucleotide kinase activity	1.739613580002	bayes_pls_golite062009
ATP-dependent polynucleotide kinase activity	1.739613580002	bayes_pls_golite062009
binding	1.46180911639784	bayes_pls_golite062009
catalytic activity	0.368034275052766	bayes_pls_golite062009
nuclease activity	0.36330480698384	bayes_pls_golite062009
protein binding	0.224535421875415	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: