YRC Public Data Repository - Protein Structure Prediction

Protein:	mrpl3
Organism:	Schizosaccharomyces pombe
Length:	326 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mrpl3.

Description	E-value	Query Range	Subject Range
gi\|255313919 - gi\|255313919\|ref\|ZP_05355502.1\| ribonuclease III [Clostridium difficile QCD-76w55] gi\|115250281, gi... - gi\|126698844\|ref\|YP_001087741.1\| putative ribonuclease III [Clostridium difficile 630], gi\|115250281... gi\|255516598 - gi\|255516598\|ref\|ZP_05384274.1\| ribonuclease III [Clostridium difficile QCD-97b34] gi\|255649698 - gi\|255649698\|ref\|ZP_05396600.1\| ribonuclease III [Clostridium difficile QCD-37x79] gi\|254974792 - gi\|254974792\|ref\|ZP_05271264.1\| ribonuclease III [Clostridium difficile QCD-66c26] gi\|255092180 - gi\|255092180\|ref\|ZP_05321658.1\| ribonuclease III [Clostridium difficile CIP 107932] gi\|90575136, gi\|... - gi\|90575136\|ref\|ZP_01231621.1\| hypothetical protein CdifQ_02001248 [Clostridium difficile QCD-32g58]... gi\|255100264 - gi\|255100264\|ref\|ZP_05329241.1\| ribonuclease III [Clostridium difficile QCD-63q42] gi\|255306204 - gi\|255306204\|ref\|ZP_05350376.1\| ribonuclease III [Clostridium difficile ATCC 43255]	225.0	[0..40]	[283..4]
gi\|88912195, gi\|... - gi\|88931924\|ref\|ZP_01137617.1\| Ribonuclease III [Acidothermus cellulolyticus 11B], gi\|88912195\|gb\|EA...	223.0	[0..7]	[284..100]
gi\|62128779, gi\|... - gi\|62181146\|ref\|YP_217563.1\| ribonuclease III [Salmonella enterica subsp. enterica serovar Choleraes...	222.0	[0..47]	[287..25]
gi\|91227852, gi\|... - gi\|91227852\|ref\|ZP_01262025.1\| ribonuclease III [Vibrio alginolyticus 12G01], gi\|91188362\|gb\|EAS7465...	222.0	[0..45]	[284..3]
gi\|194538394, gi... - gi\|75854070\|ref\|ZP_00761790.1\| COG0571: dsRNA-specific ribonuclease [Vibrio sp. Ex25], gi\|254230524\|...	222.0	[0..45]	[284..3]
gi\|153839958, gi... - gi\|153839958\|ref\|ZP_01992625.1\| ribonuclease III [Vibrio parahaemolyticus AQ3810], gi\|149746517\|gb\|E... RNC_VIBPA - Ribonuclease 3 OS=Vibrio parahaemolyticus GN=rnc PE=3 SV=1 RNC_VIBPA - Ribonuclease 3 OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) GN=rnc PE=3 SV=1	221.0	[0..45]	[284..3]
RNC_GEOKA - Ribonuclease 3 OS=Geobacillus kaustophilus (strain HTA426) GN=rnc PE=3 SV=1 RNC_GEOKA - Ribonuclease 3 OS=Geobacillus kaustophilus GN=rnc PE=3 SV=1	220.0	[0..45]	[284..16]
RNC_VIBTL - Ribonuclease 3 OS=Vibrio tasmaniensis (strain LGP32) GN=rnc PE=3 SV=1 gi\|84376758, gi\|... - gi\|84390104\|ref\|ZP_00991366.1\| ribonuclease III [Vibrio splendidus 12B01], gi\|84376758\|gb\|EAP93633.1... gi\|86146359, gi\|... - gi\|86146359\|ref\|ZP_01064683.1\| ribonuclease III [Vibrio sp. MED222], gi\|85835838\|gb\|EAQ53972.1\| ribo...	220.0	[0..45]	[285..3]
RNC_LISMO - Ribonuclease 3 OS=Listeria monocytogenes GN=rnc PE=3 SV=1 RNC_LISMO - Ribonuclease 3 OS=Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) GN=rnc PE=3 SV=1 gi\|224501394 - gi\|224501394\|ref\|ZP_03669701.1\| ribonuclease III [Listeria monocytogenes FSL R2-561]	219.0	[0..48]	[284..5]
gi\|153183297, gi... - gi\|254899498\|ref\|ZP_05259422.1\| ribonuclease III [Listeria monocytogenes J0161], gi\|153183297\|ref\|ZP... gi\|127765093, gi... - gi\|254912363\|ref\|ZP_05262375.1\| ribonuclease III [Listeria monocytogenes J2818], gi\|153191314\|ref\|ZP... gi\|153175037, gi... - gi\|254829200\|ref\|ZP_05233887.1\| ribonuclease III [Listeria monocytogenes FSL N3-165], gi\|153175037\|r... gi\|254872588 - gi\|254872588\|ref\|ZP_05245298.1\| ribonuclease III [Listeria monocytogenes FSL N1-017] gi\|47097388, gi\|... - gi\|47097388\|ref\|ZP_00234939.1\| ribonuclease III [Listeria monocytogenes str. 1/2a F6854], gi\|4701423... gi\|153179844, gi... - gi\|254936690\|ref\|ZP_05268387.1\| ribonuclease III [Listeria monocytogenes F6900], gi\|153179844\|ref\|ZP... RNC_LISMH - Ribonuclease 3 OS=Listeria monocytogenes serotype 4a (strain HCC23) GN=rnc PE=3 SV=1	219.0	[0..48]	[284..5]

Back

Predicted Domain #1

Region A:
Residues: [1-326]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFISRSTTT FRRSISMKDY ARVRWYSNSG KSLIENILSS KIAISKVYTL KKRIGLPESY  60
   61 PMKVLVQALI DKTVVQNPQY SNEKLWSIGK VFGDFYVLEY IKCKYPRLPE EAVHGMQNGW 120
  121 MGSKALSQLA TIWGLEVQRR EEGLQESFGK VLAKRADPEM LRKPGEIYKD EAARRAILAI 180
  181 LGGVYLHQGF NDTKKFINDH ILSKQLDPRT MLQLQWPRRQ LSRLCKRLSL KEPVYRIIAE 240
  241 TGRKSREPVF VIGAYSGHHL LGQGQASSLN LAEQQAAYNS LISYYIHSPP FRQLPSDYLE 300
  301 VNDGKIPKAS EPYTSIPLVS HGQLVI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	51.39794
Match:	1o0wA
Description:	RNase III endonuclease catalytic domain; RNase III, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
structural constituent of ribosome	6.7575603459566	bayes_pls_golite062009
structural molecule activity	6.24187874355454	bayes_pls_golite062009
RNA binding	5.07736605479017	bayes_pls_golite062009
nucleic acid binding	2.45216687077957	bayes_pls_golite062009
binding	2.27335967900422	bayes_pls_golite062009
endoribonuclease activity	1.62086478301433	bayes_pls_golite062009
double-stranded RNA binding	1.46317494664076	bayes_pls_golite062009
DNA binding	0.770826702436345	bayes_pls_golite062009
protein binding	0.736755095770059	bayes_pls_golite062009
transcription regulator activity	0.661231648959158	bayes_pls_golite062009
mRNA binding	0.404665180963566	bayes_pls_golite062009
single-stranded RNA binding	0.35650576095599	bayes_pls_golite062009
RNA helicase activity	0.0112094156505713	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: