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View Structure Prediction Details

Protein: mde4
Organism: Schizosaccharomyces pombe
Length: 421 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mde4.

Description E-value Query
Range
Subject
Range
KRT84 - keratin 84
144.0 [0..2] [267..232]
gi|68388302 - gi|68388302|ref|XP_696268.1| PREDICTED: similar to slow myosin heavy chain 1 [Danio rerio]
136.0 [0..14] [379..2379]
gi|109096767 - gi|109096767|ref|XP_001093322.1| PREDICTED: similar to keratin, hair, basic, 3 [Macaca mulatta]
131.0 [0..5] [267..181]
gi|4103156 - gi|4103156|gb|AAD01692.1| hair keratin basic 5; keratin Hb5 [Mus musculus]
131.0 [0..5] [267..193]
gi|114625886 - gi|114625886|ref|XP_520149.2| PREDICTED: similar to OTTHUMP00000021786 [Pan troglodytes]
129.0 [0..4] [267..439]
gi|115496498, gi... - gi|76617959|ref|XP_606882.2| PREDICTED: similar to keratin, hair, basic, 5 [Bos taurus], gi|11549649...
124.0 [0..5] [267..193]
gi|73996366 - gi|73996366|ref|XP_860589.1| PREDICTED: similar to type II keratin Kb21 isoform 3 [Canis familiaris]
124.0 [0..29] [267..160]

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Predicted Domain #1
Region A:
Residues: [1-338]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTISTSTDS KLDNLGLSVT SRRNQILFYL SKALNLAHLL RSDSLQKSFL DALKQSATDS  60
   61 ELLHKNLDEI KFLQNEKLNN EKLLEQEQNE ANDYRLKVER LEHKISDYVQ EINSLNSQLQ 120
  121 IQKSNPEKHE DAVSQNRLRG SLDTVSSPSK THKANKDEKA TRLHLIIANL KKALKEKDAE 180
  181 VLNLQSHVSS KESELDRFKI KLETEESNWK VRLQVLESKL ATQDRKLRMQ KKSTERKSLL 240
  241 VSPRVSSPKL FSPSKQAIMG TRQPNATSGS PLSVTPFLQK TSTSIGLSSS PPQSSPSAQS 300
  301 SQPFSRDKYP HSMTVSPSNA RYLKKHLDDT IPSNVSDI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.30103
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [339-421]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NHNDHLKIPQ SPSSLSPSKI PIRKKRKLKD TVSNCEFTEE DSESSFLLET IQPTKSTLRR  60
   61 SISPLKKRND EINELKKGFT MKK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle