YRC Public Data Repository - Protein Structure Prediction

Protein:	coq5
Organism:	Schizosaccharomyces pombe
Length:	305 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for coq5.

Description	E-value	Query Range	Subject Range
gi\|21483356 - gi\|21483356\|gb\|AAM52653.1\| GM25741p [Drosophila melanogaster]	226.0	[0..1]	[305..6]
gi\|49529619, gi\|... - gi\|50083643\|ref\|YP_045153.1\| S-adenosylmethionine: 2-DMK methyltransferase and 2-octaprenyl-6-methox...	222.0	[0..21]	[305..52]
gi\|71038264, gi\|... - gi\|71065279\|ref\|YP_264006.1\| 2-octaprenyl-6-methoxy-1,4-benzoquinone methylase / demethylmenaquinone...	222.0	[0..39]	[304..122]
UBIE_VIBCH - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Vibrio cholerae serotype O1 (strain ... UBIE_VIBCM - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Vibrio cholerae serotype O1 (strain ... gi\|229508366, gi... - gi\|229508366\|ref\|ZP_04397870.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|229346129, gi... - gi\|229517066\|ref\|ZP_04406512.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|229520118, gi... - gi\|229520118\|ref\|ZP_04409546.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|229527169, gi... - gi\|229527169\|ref\|ZP_04416563.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|229369296, gi... - gi\|229606641\|ref\|YP_002877289.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vi... gi\|121587669, gi... - gi\|121587669\|ref\|ZP_01677432.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|124115249, gi... - gi\|153214643\|ref\|ZP_01949519.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|254851469, gi... - gi\|75829374\|ref\|ZP_00758679.1\| COG2226: Methylase involved in ubiquinone/menaquinone biosynthesis [V... gi\|153222877, gi... - gi\|153222877\|ref\|ZP_01953501.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|153801700, gi... - gi\|153801700\|ref\|ZP_01956286.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|116216422, gi... - gi\|75823221\|ref\|ZP_00752740.1\| COG2226: Methylase involved in ubiquinone/menaquinone biosynthesis [V... gi\|153818222, gi... - gi\|153818222\|ref\|ZP_01970889.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... UBIE_VIBC3 - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Vibrio cholerae serotype O1 (strain ... gi\|126520347, gi... - gi\|229508952\|ref\|ZP_04398442.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|121727801, gi... - gi\|75816414\|ref\|ZP_00746885.1\| COG2226: Methylase involved in ubiquinone/menaquinone biosynthesis [V... gi\|254291829, gi... - gi\|254291829\|ref\|ZP_04962613.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|153829106, gi... - gi\|153829106\|ref\|ZP_01981773.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... UBIE_VIBCH - Ubiquinone/menaquinone biosynthesis methyltransferase ubiE OS=Vibrio cholerae GN=ubiE PE=3 SV=1 gi\|149739586, gi... - gi\|153826648\|ref\|ZP_01979315.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c...	221.0	[0..33]	[304..2]
gi\|194537307, gi... - gi\|75820016\|ref\|ZP_00750074.1\| COG2226: Methylase involved in ubiquinone/menaquinone biosynthesis [V...	220.0	[0..33]	[304..2]
UBIE_VIBVU - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Vibrio vulnificus (strain CMCP6) GN=... UBIE_VIBVY - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Vibrio vulnificus (strain YJ016) GN=... UBIE_VIBVU - Ubiquinone/menaquinone biosynthesis methyltransferase ubiE OS=Vibrio vulnificus GN=ubiE PE=3 SV=1	220.0	[0..36]	[304..5]
gi\|92393196, gi\|... - gi\|93005518\|ref\|YP_579955.1\| ubiquinone/menaquinone biosynthesis methyltransferases [Psychrobacter c...	220.0	[0..39]	[304..110]
gi\|84386296, gi\|... - gi\|84386296\|ref\|ZP_00989324.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Vibrio splendi...	220.0	[0..34]	[304..8]
gi\|218321183, gi... - gi\|218708164\|ref\|YP_002415785.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Vibrio splen... gi\|85835662, gi\|... - gi\|86146605\|ref\|ZP_01064927.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Vibrio sp. MED...	219.0	[0..34]	[304..8]

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Predicted Domain #1

Region A:
Residues: [1-305]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRLRAPVAK FLADGLKGIR STALAGSRLS NCRYTSTSSK DTDTSSHMTH FGFKDVPEDE  60
   61 KEHLVKNVFS SVAKKYDEMN DAMSLGIHRL WKNIFVSRLN PGNSTVPMKI LDVAGGTGDI 120
  121 AFRILNHATN HNGDRNTRVI VADINPDMLS VGLRRSKKTP YYDSGRVEFI EQNAEILDKI 180
  181 PDNSIDMYTI AFGIRNCTHI PKVLEQAYRV LKPGGVFSCL EFSKVYPAPL AELYRQYSFK 240
  241 ILPLLGTIIA GDSQSYEYLV ESIERFPDAK TFAKMIEDAG FTLAGETGYE TLSFGIAAIH 300
  301 TGIKL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	10.69897
Match:	1qzzA
Description:	Crystal structure of aclacinomycin-10-hydroxylase (RdmB) in complex with S-adensyl-L-methionine (SAM)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.25333584501255	bayes_pls_golite062009
transferase activity	1.07321114919891	bayes_pls_golite062009
oxidoreductase activity	0.964067575431689	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	0.612108481676679	bayes_pls_golite062009
methyltransferase activity	0.606225212585352	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	0.14147363365106	bayes_pls_golite062009
binding	0.109975487409217	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: