YRC Public Data Repository - Protein Structure Prediction

Protein:	sen34
Organism:	Schizosaccharomyces pombe
Length:	284 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sen34.

Description	E-value	Query Range	Subject Range
gi\|42550758, gi\|... - gi\|46116866\|ref\|XP_384451.1\| hypothetical protein FG04275.1 [Gibberella zeae PH-1], gi\|42550758\|gb\|E...	264.0	[0..2]	[281..5]
gi\|49084222, gi\|... - gi\|67515817\|ref\|XP_657794.1\| hypothetical protein AN0190.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	247.0	[0..3]	[274..6]
gi\|114190245, gi... - gi\|115401432\|ref\|XP_001216304.1\| conserved hypothetical protein [Aspergillus terreus NIH2624], gi\|11...	243.0	[0..3]	[282..6]
SEN34_NEUCR - Probable tRNA-splicing endonuclease subunit tsp-4 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-... SEN34_NEUCR, SE3... - Probable tRNA-splicing endonuclease subunit sen-34 OS=Neurospora crassa GN=sen-34 PE=3 SV=1, (Q7SAK9...	241.0	[0..2]	[282..6]
gi\|83770002 - gi\|83770002\|dbj\|BAE60137.1\| unnamed protein product [Aspergillus oryzae] gi\|169775343 - gi\|169775343\|ref\|XP_001822139.1\| hypothetical protein [Aspergillus oryzae RIB40]	233.0	[0..5]	[282..8]
gi\|70997583, gi\|... - gi\|70997583\|ref\|XP_753534.1\| tRNA-splicing endonuclease subunit sen34 [Aspergillus fumigatus Af293],...	232.0	[0..3]	[282..6]
gi\|119192574, gi... - gi\|90305679\|gb\|EAS35310.1\| hypothetical protein CIMG_00664 [Coccidioides immitis RS], gi\|119192574\|r...	229.0	[0..5]	[282..26]
gi\|109126016, gi... - gi\|109126022\|ref\|XP_001082500.1\| PREDICTED: tRNA splicing endonuclease 34 homolog (SEN34, S. cerevis...	228.0	[0..8]	[281..4]
gi\|114679004, gi... - gi\|114679014\|ref\|XP_001174914.1\| PREDICTED: hypothetical protein isoform 2 [Pan troglodytes], gi\|114... TSEN34 - tRNA splicing endonuclease 34 homolog (S. cerevisiae)	227.0	[0..8]	[281..4]
gi\|10438595 - gi\|10438595\|dbj\|BAB15284.1\| unnamed protein product [Homo sapiens]	226.0	[0..8]	[281..4]

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Predicted Domain #1

Region A:
Residues: [1-105]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEDEKFPISY VHGKFLVFDV QAVEVFRKNY HILGTLVGTL PQLPQQNVFL GLPMELSKEE  60
   61 AFYLIEKGIS YIVDDTKVHK QLLENTTKDD VKQCLKKRQS LAYDQ

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.447	0.707	mitochondrial outer membrane	f.1.4	Bcl-2 inhibitors of programmed cell death
View	Download	0.424	0.090	tRNA-intron endonuclease activity	a.45.1	Glutathione S-transferase (GST), C-terminal domain
View	Download	0.481	0.021	tRNA-intron endonuclease activity	c.51.1	Anticodon-binding domain of Class II aaRS
View	Download	0.455	0.006	tRNA-intron endonuclease activity	a.24.11	Bacterial GAP domain
View	Download	0.454	N/A	N/A	c.23.12	Formate/glycerate dehydrogenase catalytic domain-like

Predicted Domain #2

Region A:
Residues: [106-284]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIAAKKKENE KKIEIMKKLG RTLPLDPLNY DEHDSFDLSW IPVDTVTTRI AEKSSMNDDF  60
   61 HKEEDVFENL DINRYLMFKS LVDTGFYLNP GLRFGCQFVA YPGDALRYHS HYLVNSYKWD 120
  121 QEIPVLFLIG GGRLGTAVKK TWLIGGSNDR NINMNGEKSK EELLLLPVRH FSIEWAGFG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	28.522879
Match:	2cv8A
Description:	Crystal structure of tRNA-intron endonuclease from Sulfolobus tokodaii
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits