YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC9G1.08c
Organism:	Schizosaccharomyces pombe
Length:	241 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC9G1.08c.

Description	E-value	Query Range	Subject Range
gi\|39795561, gi\|... - gi\|45361419\|ref\|NP_989287.1\| hypothetical protein LOC394905 [Xenopus (Silurana) tropicalis], gi\|3979...	197.0	[0..1]	[226..1]
gi\|41152185, gi\|... - gi\|41152185\|ref\|NP_957043.1\| lysophospholipase II [Danio rerio], gi\|37748063\|gb\|AAH59556.1\| Zgc:7321...	197.0	[0..1]	[226..1]
gi\|148225532, gi... - gi\|27881717\|gb\|AAH44315.1\| MGC52664 protein [Xenopus laevis], gi\|148225532\|ref\|NP_001079559.1\| simil...	195.0	[0..1]	[226..1]
LYPA2_RAT - Acyl-protein thioesterase 2 OS=Rattus norvegicus GN=Lypla2 PE=1 SV=1	194.0	[0..1]	[227..1]
gi\|109086409 - gi\|109086409\|ref\|XP_001083287.1\| PREDICTED: lysophospholipase I isoform 2 [Macaca mulatta]	194.0	[0..1]	[227..1]
LYPA1_PONPY - Acyl-protein thioesterase 1 - Pongo pygmaeus (Orangutan) LYPA1_PONAB - Acyl-protein thioesterase 1 OS=Pongo abelii GN=LYPLA1 PE=2 SV=1	194.0	[0..1]	[227..1]
gi\|114620143 - gi\|114620143\|ref\|XP_519760.2\| PREDICTED: hypothetical protein isoform 4 [Pan troglodytes]	193.0	[0..1]	[227..1]
gi\|123996083, gi... - gi\|123996083\|gb\|ABM85643.1\| lysophospholipase I [synthetic construct], gi\|123981248\|gb\|ABM82453.1\| l... LYPLA1 - lysophospholipase I	193.0	[0..1]	[227..1]
gi\|119936523, gi... - gi\|122692349\|ref\|NP_001073831.1\| lysophospholipase II [Bos taurus], gi\|119936523\|gb\|ABM06143.1\| lyso...	192.0	[0..1]	[227..1]
LYPA2_MOUSE - Acyl-protein thioesterase 2 OS=Mus musculus GN=Lypla2 PE=1 SV=1	192.0	[0..1]	[227..1]

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Predicted Domain #1

Region A:
Residues: [1-241]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSLNSVLPS NACAEIIEGK DKVHNVVILM HGLGDSHKSF ANMAKNVPLP NTSYISLRGP  60
   61 YRLPLDFENP GGNWMWGEDV HFDQNGELQS EADFSKSFTM ISNLIGNLLS YGILSSRIFF 120
  121 FGFGQGAMVA LYSCYKLSTK YQLGGIFSFG GTLPLSITLP NHPFHVPVYL FEKRLHCSCS 180
  181 EYEESRLRKT FKPFHLTCWN RDDKTDMPSS PREWYTFVQS ISKHLYIHNT LFEDAIPLTS 240
  241 F

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	46.221849
Match:	1fj2A
Description:	Acyl protein thioesterase 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrolase activity	1.75934962198703	bayes_pls_golite062009
catalytic activity	1.39629727416851	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	1.09488027320166	bayes_pls_golite062009
lipase activity	0.849473630399459	bayes_pls_golite062009
carboxylesterase activity	0.424330502936163	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: