YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC4F8.04
Organism:	Schizosaccharomyces pombe
Length:	306 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC4F8.04.

Description	E-value	Query Range	Subject Range
gi\|50751392 - gi\|50751392\|ref\|XP_422376.1\| PREDICTED: similar to RNA processing factor 1 [Gallus gallus]	309.0	[0..2]	[306..272]
IMP4_YARLI - U3 small nucleolar ribonucleoprotein protein IMP4 OS=Yarrowia lipolytica GN=IMP4 PE=3 SV=1 IMP4_YARLI - U3 small nucleolar ribonucleoprotein protein IMP4 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) G...	293.0	[0..1]	[306..1]
gi\|110645366, gi... - gi\|89272523\|emb\|CAJ83459.1\| brix domain containing 5 [Xenopus tropicalis], gi\|110645366\|gb\|AAI18765....	292.0	[0..1]	[306..47]
gi\|62644541, gi\|... - gi\|62644541\|ref\|XP_575059.1\| PREDICTED: similar to Ribosome production factor 1 (Ribosome biogenesis...	291.0	[0..1]	[306..72]
gi\|109008739, gi... - gi\|109008739\|ref\|XP_001106723.1\| PREDICTED: similar to RNA processing factor 1 isoform 3 [Macaca mul...	290.0	[0..1]	[306..54]
RPF1 - ribosome production factor 1 homolog (S. cerevisiae) gi\|114557449 - gi\|114557449\|ref\|XP_524755.2\| PREDICTED: hypothetical protein isoform 2 [Pan troglodytes]	289.0	[0..1]	[306..54]
gi\|7268199, gi\|5... - gi\|7268199\|emb\|CAB77726.1\| hypothetical protein [Arabidopsis thaliana], gi\|58652114\|gb\|AAW80882.1\| A...	288.0	[0..2]	[306..37]
gi\|49643437 - gi\|49643437\|emb\|CAG99389.1\| KLLA0E07833p [Kluyveromyces lactis] gi\|49643437, gi\|... - gi\|50308599\|ref\|XP_454302.1\| unnamed protein product [Kluyveromyces lactis], gi\|49643437\|emb\|CAG9938...	288.0	[0..1]	[306..1]
gi\|57088279 - gi\|57088279\|ref\|XP_537096.1\| PREDICTED: similar to RNA processing factor 1 [Canis familiaris]	288.0	[0..1]	[306..54]

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Predicted Domain #1

Region A:
Residues: [1-89]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKIKNKIVR QQQYMKALHQ KNKDKLERRK ERAKEEEKDP EKKRLRLSEN IPATIESKRV  60
   61 YDETIIEDKP DEELQAELKD DEFSAYFSE

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.711	0.155	ribosomal large subunit assembly	a.61.1	Retroviral matrix proteins
View	Download	0.496	0.048	ribosomal large subunit assembly	a.60.6	DNA polymerase beta, N-terminal domain-like
View	Download	0.545	0.026	ribosomal large subunit assembly	a.71.1	Endoplasmic reticulum protein ERP29, C-domain
View	Download	0.471	N/A	N/A	a.71.1	Endoplasmic reticulum protein ERP29, C-domain
View	Download	0.457	N/A	N/A	a.60.6	DNA polymerase beta, N-terminal domain-like

Predicted Domain #2

Region A:
Residues: [90-184]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ERKVPKLLVT TSKRASRKCY DFASELLDCF PNAEFRKRTG DIEVHEIAEA AAKRGYTDLL  60
   61 VLNEDRKKTN ALTLVHLPNG PSFYFTLSNL QTAKE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	14.045757
Match:	2cxhA
Description:	Crystal structure of probable ribosomal biogenesis protein from Aeropyrum pernix K1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
aminoacyl-tRNA ligase activity	3.58650371779212	bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds	3.58624422951947	bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds	3.58624422951947	bayes_pls_golite062009
ligase activity	2.44518871945794	bayes_pls_golite062009
proline-tRNA ligase activity	2.35871952544841	bayes_pls_golite062009
binding	1.78917266819015	bayes_pls_golite062009
catalytic activity	0.902495165806215	bayes_pls_golite062009
protein binding	0.665778090365515	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [185-306]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ISNHGRSTGH IPELIINNFS TRLGMTVARA FQSLFIQTPQ IQGRQVVTIH CQRDFLFFRR  60
   61 HRYAFREKSN MPDGIGTGLQ ELGPRFTMRL RMVQKGVWDR KEGEVFFESN AGEESDRRKF 120
  121 WL

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.82
Match:	2cxhA
Description:	Crystal structure of probable ribosomal biogenesis protein from Aeropyrum pernix K1
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: