YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC12B10.04
Organism:	Schizosaccharomyces pombe
Length:	403 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC12B10.04.

Description	E-value	Query Range	Subject Range
gi\|114686766 - gi\|114686766\|ref\|XP_001171605.1\| PREDICTED: tubulin tyrosine ligase-like family, member 1 isoform 3 ...	370.0	[0..12]	[398..5]
TTLL1_MOUSE - Probable tubulin polyglutamylase TTLL1 OS=Mus musculus GN=Ttll1 PE=1 SV=1	368.0	[0..12]	[398..5]
TTLL1_RAT - Probable tubulin polyglutamylase TTLL1 OS=Rattus norvegicus GN=Ttll1 PE=2 SV=1	368.0	[0..12]	[398..5]
TTLL1_BOVIN - Probable tubulin polyglutamylase TTLL1 OS=Bos taurus GN=TTLL1 PE=2 SV=1	367.0	[0..12]	[398..5]
gi\|73968917 - gi\|73968917\|ref\|XP_848798.1\| PREDICTED: similar to tubulin tyrosine ligase-like family, member 1 iso...	366.0	[0..12]	[398..5]
gi\|114686762, gi... - gi\|114686764\|ref\|XP_001171655.1\| PREDICTED: tubulin tyrosine ligase-like family, member 1 isoform 6 ... gi\|123982766, gi... - gi\|123997435\|gb\|ABM86319.1\| tubulin tyrosine ligase-like family, member 1 [synthetic construct], gi\|... HGNC:1312\|MIM:60... - tyrosine ligase-like family, member 1 TTLL1 - tubulin tyrosine ligase-like family, member 1	365.0	[0..12]	[398..5]
gi\|42553151, gi\|... - gi\|46136001\|ref\|XP_389692.1\| hypothetical protein FG09516.1 [Gibberella zeae PH-1], gi\|42553151\|gb\|E...	353.0	[0..8]	[392..322]

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Predicted Domain #1

Region A:
Residues: [1-403]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSTKKDIKV YVNYRDEYAE PKIISALKNS GKELTFTNSA KEANFQWAQY EDIDFDEVYK  60
   61 NPKTKLCCSY VIRKALIRKE YLWRTVITYL AKHPDSILSK SVPEAYSLEL DYAEFLDDSL 120
  121 MEAYELRQEL EENATKNISE KQWYILKPSM CDRAQGIRLF STIEELQAIF DSFDDEESES 180
  181 EEAGLEEKGD ITVAFNNKIV ISQIRNFLVQ KYISKPLLLD HRKFHIRAYV LATGALSVYL 240
  241 FNEMLCLLAR DKYKKPTPDP DLLFSHLSNT CLQGDNVEQS SIRDFWNTSI ENKDDIFKSI 300
  301 LNIIGDVFEA AATTQGIHFQ PLENCFEIFG VDFLVDCESQ VYLLEVNSYP DFKQTGKNLS 360
  361 NIIENLFSAV VETAIIPFFE SSTKRNVDSK LTLAKKLQLF GFR

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.56
Match:	1uc8A
Description:	Crystal structure of a lysine biosynthesis enzyme, Lysx, from thermus thermophilus HB8
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ligase activity	2.3452449284312	bayes_pls_golite062009
catalytic activity	2.29256365911737	bayes_pls_golite062009
binding	0.69937216690755	bayes_pls_golite062009
acid-amino acid ligase activity	0.391643009882919	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.352085804409418	bayes_pls_golite062009
transferase activity	0.123556083864668	bayes_pls_golite062009
protein binding	0.1153438949594	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: