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View Structure Prediction Details

Protein: ucp6
Organism: Schizosaccharomyces pombe
Length: 612 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

No multiple sequence alignment data found for ucp6.

Predicted Domain #1
Region A:
Residues: [1-79]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEDLDTKIKT LKNMGVSESD AKDSLERCGY DVESAAEFIF SGQLEKSRLV PIMSSTSIAS  60
   61 SLPSYQDTFF LPSPRKRRR

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.1
Match: 1vegA
Description: Solution Structure of RSGI RUH-012, a UBA Domain from Mouse cDNA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
small conjugating protein-specific protease activity 2.71271041474697 bayes_pls_golite062009
ubiquitin-specific protease activity 2.60822531662407 bayes_pls_golite062009
cysteine-type peptidase activity 1.89678318965687 bayes_pls_golite062009
binding 1.771454265561 bayes_pls_golite062009
protein binding 1.15277727477352 bayes_pls_golite062009
nucleic acid binding 0.605372479737519 bayes_pls_golite062009
ubiquitin binding 0.319972124839967 bayes_pls_golite062009
catalytic activity 0.2736776367506 bayes_pls_golite062009
DNA binding 0.231060944599623 bayes_pls_golite062009
transcription regulator activity 0.198503229187597 bayes_pls_golite062009
small conjugating protein binding 0.148403739682047 bayes_pls_golite062009
enzyme binding 0.133222626367861 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [80-160]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPGRIGTVLK PSALFPAIAP FLFVVFEIPV ALNTFVHATC KGLLFAEDNA SFHRPFTDVS  60
   61 AHLSSSSLSK YNHHSNHRLA S

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [161-315]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PGWWYGEDSC ISQSLDPRSV MQVQTIRAFE FLFSSHRLYL DTVHITAALS QVLAGLGNTN  60
   61 TSMSDGDCIA AFLSSYFSPP NAEFDSTFCS TLSSLTNSEK PTYIFNFKPN STPDLRLSIE 120
  121 SCLDLLLHPP SSAQKNWSWI KHVGKVFCCS LPGNN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [316-612]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASGTPRFLLT PKIDLSKCII ENRDEMLRRY QLETVYRKTL LEWEDLYKRL TGVTLTDKDI  60
   61 GELLTDGQQF LEKRNPALSS HLQLLKETLQ TKISTLISNT NATQHKLSTL YRGMQNKCTR 120
  121 RLLAVIIEPS IIYICLKNSA VQSNRNVSPS ANHNEQWYLV RFTTSATISQ DSPPCIVEPV 180
  181 TFEEVDLEFE KHISYHNRLL IYVDDDCEAS TRTVIPTSVK NFIAEDNEYF DDELAGIIHS 240
  241 PTVSTRSSRS SDVSEYDLED QGGLQLTVPH INTDVQCHRS RNSACEFPES MHVEHSG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle