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View Structure Prediction Details

Protein: SPAC22G7.07c
Organism: Schizosaccharomyces pombe
Length: 413 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC22G7.07c.

Description E-value Query
Range
Subject
Range
gi|7267694, gi|7... - pir||T04002 hypothetical protein T5L19.110 - Arabidopsis thaliana, gi|7267694|emb|CAB78121.1| putati...
294.0 [0..167] [411..567]
gi|74002408 - gi|74002408|ref|XP_545043.2| PREDICTED: similar to CG7818-PA [Canis familiaris]
292.0 [0..149] [411..190]
gi|113532213, gi... - gi|215694337|dbj|BAG89330.1| unnamed protein product [Oryza sativa Japonica Group], gi|115435848|ref...
291.0 [0..167] [411..457]
METL4_MOUSE - Methyltransferase-like protein 4 OS=Mus musculus GN=Mettl4 PE=2 SV=1
290.0 [0..138] [410..189]
gi|187469693, gi... - gi|34859963|ref|XP_215698.2| PREDICTED: similar to CG7818-PA [Rattus norvegicus], gi|187469693|gb|AA...
289.0 [0..149] [411..101]
gi|109075492 - gi|109075492|ref|XP_001098431.1| PREDICTED: similar to CG7818-PA [Macaca mulatta]
288.0 [0..149] [411..101]
gi|114595809 - gi|114595809|ref|XP_517408.2| PREDICTED: similar to KIAA1627 protein [Pan troglodytes]
gi|168270634 - gi|168270634|dbj|BAG10110.1| KIAA1627 protein [synthetic construct]
MET14_PONAB - N6-adenosine-methyltransferase subunit METTL14 OS=Pongo abelii GN=METTL14 PE=2 SV=1
gi|55732463 - gi|55732463|emb|CAH92932.1| hypothetical protein [Pongo abelii]
METTL14 - methyltransferase like 14
287.0 [0..149] [411..101]

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Predicted Domain #1
Region A:
Residues: [1-166]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDTSCLIDL PTSLQFNKHI LPTRTKPVVK PYLLPEKSTS DYENSGKGTV GQVLQSLQRV  60
   61 RRALQLRSLD DNQSTDKSHH VQFQDIVYRS NTSASEIHFQ AENAPLVQWY SDIFKVLVKA 120
  121 PVIQFEDQCL QWLKMLNTIP PSYSFITIKS KDTVELGLEE IYQQCV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [167-413]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QNDGASAIKL KLKGSKVITE SSETNCRDSI YYIPARSSFI MGDVEKTAQI LLEAIDGHLE  60
   61 KPKCIIIDPP WPNKSVARSS VYKVNRNLGY LKALPIQESL SKTGVVAVWC TNKEKYVNFV 120
  121 KKVLFKKWNL TLVSTWTWLK ITAFGEPLFD VYSNMRKPWE QLLIGVTSEY TSVYSDKIPP 180
  181 TFTIIGIPDY HSRKPSLKPF ISRWFNCSAN ESLPVLEIFG RSLTPNWITW GREPLLFMHE 240
  241 LYWSSDN

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.18
Match: 1eg2A
Description: m.RsrI N6 adenosine-specific DNA methyltransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
methyltransferase activity 3.10667683620555 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 3.03092170856472 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 2.91374296950366 bayes_pls_golite062009
transferase activity 2.67612625778122 bayes_pls_golite062009
RNA methyltransferase activity 2.63941856307703 bayes_pls_golite062009
rRNA methyltransferase activity 1.85380504590369 bayes_pls_golite062009
catalytic activity 1.16970557486814 bayes_pls_golite062009
tRNA methyltransferase activity 0.752031224323003 bayes_pls_golite062009
RNA binding 0.591792136535375 bayes_pls_golite062009
N-methyltransferase activity 0.458289303306923 bayes_pls_golite062009
protein binding 0.22496630724233 bayes_pls_golite062009
rRNA (adenine) methyltransferase activity 0.113328595762489 bayes_pls_golite062009
rRNA (adenine-N6,N6-)-dimethyltransferase activity 0.0390774859535424 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle