YRC Public Data Repository - Protein Structure Prediction

Protein:	vps35
Organism:	Schizosaccharomyces pombe
Length:	785 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for vps35.

Description	E-value	Query Range	Subject Range
gi\|47212853 - gi\|47212853\|emb\|CAF93242.1\| unnamed protein product [Tetraodon nigroviridis]	1070.0	[0..1]	[737..472]
gi\|109150097 - gi\|109150097\|gb\|AAI17574.1\| Zgc:136268 protein [Danio rerio]	1060.0	[0..1]	[737..53]
gi\|147904796, gi... - gi\|58618878\|gb\|AAH89195.1\| MGC98309 protein [Xenopus laevis], gi\|147904796\|ref\|NP_001089981.1\| hypot...	1047.0	[0..1]	[739..53]
gi\|114662323, gi... - gi\|114662323\|ref\|XP_001161400.1\| PREDICTED: vacuolar protein sorting 35 isoform 4 [Pan troglodytes],...	1039.0	[0..1]	[737..14]
VPS35_MOUSE - Vacuolar protein sorting-associated protein 35 OS=Mus musculus GN=Vps35 PE=1 SV=1	1039.0	[0..1]	[737..53]
gi\|9622850 - gi\|9622850\|gb\|AAF89953.1\|AF175265_1 vacuolar sorting protein 35 [Homo sapiens]	1038.0	[0..1]	[737..53]

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Predicted Domain #1

Region A:
Residues: [1-785]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRNSALTPKQ YYELYMFNME SLRLLGGTLL ETHLNGTHNL MDLYELVQYA GSIVPRLYLM  60
   61 ITVGSAYLET PNALVREIMN DLLDMCRGVQ HPLRGLFLRH YLLTQTRKGL PLGSEDEEDA 120
  121 SRKGTVLDSV KFLVINFTEM NKLWVRIQHL GPIKEFSKRT QERNELKVLV GLNLVRLSQL 180
  181 NLDIDTYRDH VLPAIIEQII ECRDSLAQEY LVEVICQAFS DNMHLQTLDT YFGTVIKLSP 240
  241 SVNVTQLVVA MLNRLTDYVQ REYESDSSNE DESETVTEKL GDIKINEEVQ QKDEQECPGD 300
  301 KVIPPEYAIQ EVLWSHVVEV IQSRSGLPLD CIVSILSSIL NFFLRCYPYK PQYADRVFQY 360
  361 INEHIINQPS LRSALHERPL QKSLCAILLL PLTYFPSFSY CLELQNFLPV FNAQDPNLRY 420
  421 DIARMIVQKI IEKGHSLSEL TEAQELLGFV SVIIEKKGVD SLDDLQNVAL MVHYLNNDDP 480
  481 QIQIEILRSL KDTFIKAGEN VKYLLPVVVN RCIFLARNFR IFKCMDWAEK VRLLWEFVNT 540
  541 CINVLYKNGD SLELCLALYL SAAEMADQEN YPDFAYEFFT QAFSIYEESV LDSELQYQQL 600
  601 LMIIGKLQKT RNFSVDDYDT LITKCTLYAS KLLKKPDQCC GIYLASHLWW QVASGEDSRP 660
  661 FQDPKRVLEC LQKSLKIADA CMDQLTSLKL FINILERYFY YYDQHCESII AKHISGLIDL 720
  721 TEQNMRSILI SSPADLIASD PRAYASSIWE VANVSVIDSL KNHLERATAY AEKRSEDERW 780
  781 SSIFQ

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.0
Match:	1u6gA
Description:	Crystal Structure of The Cand1-Cul1-Roc1 Complex
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits