YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAP8A3.06
Organism:	Schizosaccharomyces pombe
Length:	216 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAP8A3.06.

Description	E-value	Query Range	Subject Range
gi\|82802755 - gi\|82802755\|gb\|ABB92428.1\| PABP3 [Pongo pygmaeus]	170.0	[0..8]	[213..144]
gi\|73974158 - gi\|73974158\|ref\|XP_848864.1\| PREDICTED: similar to Polyadenylate-binding protein 1 (Poly(A)-binding ...	170.0	[0..8]	[213..144]
PAB1_MOUSE, PABP... - Polyadenylate-binding protein 1 OS=Mus musculus GN=Pabpc1 PE=1 SV=1, (P29341) Polyadenylate-binding ...	170.0	[0..8]	[213..144]
PABP1_BOVIN - Polyadenylate-binding protein 1 OS=Bos taurus GN=PABPC1 PE=2 SV=1 gi\|109087089 - gi\|109087089\|ref\|XP_001098239.1\| PREDICTED: poly(A) binding protein, cytoplasmic 1 isoform 2 [Macaca... gi\|123993665, gi... - gi\|168278070\|dbj\|BAG11013.1\| polyadenylate-binding protein 1 [synthetic construct], gi\|123999981\|gb\|... gi\|194036975 - gi\|194036975\|ref\|XP_001927782.1\| PREDICTED: similar to Polyadenylate-binding protein 1 (Poly(A)-bind... PABPC1 - poly(A) binding protein, cytoplasmic 1 gi\|73974130, gi\|... - gi\|73974178\|ref\|XP_857695.1\| PREDICTED: similar to Polyadenylate-binding protein 1 (Poly(A)-binding ...	170.0	[0..8]	[213..144]

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Predicted Domain #1

Region A:
Residues: [1-151]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASHLASIYG TEQDKVNCSF YYKIGACRHG ERCSRKHVKP NFSQTILCPN MYKNPIHEPN  60
   61 GKKFTQRELA EQFDAFYEDM FCEFSKYGEV EQLVVCDNVG DHLVGNVYVR FKYEESAQNA 120
  121 IDDLNSRWYS QRPVYAELSP VTDFREACCR Q

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	9.69897
Match:	1jmtA
Description:	U2AF35 (35 KDa subunit)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
RNA binding	6.73097473547076	bayes_pls_golite062009
	6.62953239642182	bayes_pls_golite062009
mRNA binding	5.29759606920196	bayes_pls_golite062009
snRNA binding	4.06596327298973	bayes_pls_golite062009
nucleic acid binding	3.81920018903278	bayes_pls_golite062009
binding	3.49612884560266	bayes_pls_golite062009
poly-pyrimidine tract binding	3.11990160533699	bayes_pls_golite062009
U1 snRNA binding	3.02511982045347	bayes_pls_golite062009
single-stranded RNA binding	2.93798024346416	bayes_pls_golite062009
protein binding	1.32954276279597	bayes_pls_golite062009
structural molecule activity	1.29928829870122	bayes_pls_golite062009
transcription regulator activity	1.07788694919471	bayes_pls_golite062009
DNA binding	0.978604858165557	bayes_pls_golite062009
mRNA 3'-UTR binding	0.591700155096213	bayes_pls_golite062009
general RNA polymerase II transcription factor activity	0.425042944899091	bayes_pls_golite062009
transcription factor activity	0.234742017105535	bayes_pls_golite062009
snoRNA binding	0.0568636182001701	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [152-216]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HETSECQRGG LCNFMHAKKP SPQLLRDLVL AQRKYLALNA AEEMKKEPNS DSTNRWVSVT  60
   61 AERKN

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: