YRC Public Data Repository - Protein Structure Prediction

Protein:	trp4
Organism:	Schizosaccharomyces pombe
Length:	354 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for trp4.

Description	E-value	Query Range	Subject Range
gi\|196253698, gi... - gi\|196253698\|ref\|ZP_03152312.1\| anthranilate phosphoribosyltransferase [Clostridium thermocellum DSM... TRPD_CLOTH - Anthranilate phosphoribosyltransferase OS=Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / N...	408.0	[0..9]	[352..2]
TRPD_BRADU - Anthranilate phosphoribosyltransferase OS=Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 1362... TRPD_BRAJA - Anthranilate phosphoribosyltransferase OS=Bradyrhizobium japonicum GN=trpD PE=3 SV=1	382.0	[0..9]	[353..4]
TRPD_METJA - Anthranilate phosphoribosyltransferase OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 266... TRPD_METJA - Anthranilate phosphoribosyltransferase OS=Methanocaldococcus jannaschii GN=trpD PE=3 SV=1	377.0	[0..1]	[353..1]
gi\|95930492, gi\|... - gi\|95930492\|ref\|ZP_01313228.1\| anthranilate phosphoribosyltransferase [Desulfuromonas acetoxidans DS...	377.0	[0..9]	[353..2]
gi\|147920704, gi... - gi\|147920704\|ref\|YP_685492.1\| anthranilate synthase, component II (including glutamine amidotransfer...	375.0	[0..8]	[353..189]
TRPD_GEOMG - Anthranilate phosphoribosyltransferase OS=Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM...	375.0	[0..9]	[353..2]
TRPD_PSEP1 - Anthranilate phosphoribosyltransferase OS=Pseudomonas putida (strain F1 / ATCC 700007) GN=trpD PE=3 ...	374.0	[0..7]	[351..5]
TRPD_RHOP5 - Anthranilate phosphoribosyltransferase OS=Rhodopseudomonas palustris (strain BisA53) GN=trpD PE=3 SV...	373.0	[0..9]	[352..4]
TRPD_RHOPA - Anthranilate phosphoribosyltransferase OS=Rhodopseudomonas palustris GN=trpD PE=3 SV=1 trpD - trpD anthranilate phosphoribosyltransferase 3267977:3268993 forward MW:34425	372.0	[0..9]	[351..4]
TRPD_PSEPK - Anthranilate phosphoribosyltransferase OS=Pseudomonas putida (strain KT2440) GN=trpD PE=3 SV=1	372.0	[0..8]	[351..6]

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Predicted Domain #1

Region A:
Residues: [1-354]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MINTFNPEVR LAIHDLDKVG PAIPLENYEA ALRAILTGKA SPVETASFLA SLHLTKAEEV  60
   61 PDILMQTVQI LKSYSTPIAN IEMVSPRFVD IVGTGGDGHN TFNVSTASAI VAAGAGLWVC 120
  121 KHGNKASTSA SGSADLLMSF GCDLLNVTPK NIVSITEQCK FSFLFAPMCH PTLKNVAPIR 180
  181 KQLGLPTIFN LVGPLLNPIP TYARIIGVSK LSLGEVVAKT LLKLGAGRSL VVCGEEGLDE 240
  241 ISPAGPTHTW LVRDGTITHE VYTPESFHLQ SHPLSSVASG TPSANAILLE ELLSNMLHAN 300
  301 HPILDYVLMN TAALLHVAGM AESLREGVKI AQQSISSGAA LRELSNFSTI SQQP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	94.69897
Match:	1kgzA
Description:	Anthranilate phosphoribosyltransferase (TrpD)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
anthranilate phosphoribosyltransferase activity	4.81240054558791	bayes_pls_golite062009
transferase activity, transferring pentosyl groups	2.10935430322097	bayes_pls_golite062009
catalytic activity	1.99182579317454	bayes_pls_golite062009
transferase activity	1.94624792134779	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	1.10712828233974	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: