YRC Public Data Repository - Protein Structure Prediction

Protein:	tfa2
Organism:	Schizosaccharomyces pombe
Length:	285 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tfa2.

Description	E-value	Query Range	Subject Range
gi\|56377913 - gi\|56377913\|dbj\|BAD74159.1\| general transcription factor spTFIIE beta subunit [Schizosaccharomyces p...	376.0	[0..1]	[285..1]
gi\|67538656, gi\|... - gi\|67538656\|ref\|XP_663102.1\| hypothetical protein AN5498.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	315.0	[0..1]	[284..1]
gi\|44981720, gi\|... - gi\|45185930\|ref\|NP_983646.1\| ACR244Cp [Ashbya gossypii ATCC 10895], gi\|44981720\|gb\|AAS51470.1\| ACR24... gi\|44981720 - gi\|44981720\|gb\|AAS51470.1\| ACR244Cp [Ashbya gossypii ATCC 10895]	308.0	[0..1]	[282..1]
gi\|28918641, gi\|... - gi\|32405230\|ref\|XP_323228.1\| related to transcription initiation factor IIE, beta subunit [MIPS] [Ne... gi\|85085691 - gi\|85085691\|ref\|XP_957548.1\| related to transcription initiation factor IIE, beta subunit [MIPS] [Ne...	300.0	[0..2]	[284..91]
gi\|115390036, gi... - gi\|115390036\|ref\|XP_001212523.1\| conserved hypothetical protein [Aspergillus terreus NIH2624], gi\|11...	299.0	[0..1]	[284..1]
gi\|46128483, gi\|... - gi\|46128483\|ref\|XP_388795.1\| hypothetical protein FG08619.1 [Gibberella zeae PH-1], gi\|42549804\|gb\|E...	297.0	[0..1]	[284..1]
gi\|157071405, gi... - gi\|164426610\|ref\|XP_957548.2\| hypothetical protein NCU03909 [Neurospora crassa OR74A], gi\|157071405\|... gi\|16945428 - gi\|16945428\|emb\|CAB91686.2\| related to transcription initiation factor IIE, beta subunit [Neurospora...	295.0	[0..2]	[284..3]
T2EB_YEAST - Transcription initiation factor IIE subunit beta OS=Saccharomyces cerevisiae (strain ATCC 204508 / S... TFA2 - TFIIE small subunit, involved in RNA polymerase II transcription initiation gi\|151941602 - gi\|151941602\|gb\|EDN59965.1\| transcription factor TFIIE subunit [Saccharomyces cerevisiae YJM789]	290.0	[0..2]	[282..51]

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Predicted Domain #1

Region A:
Residues: [1-153]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSLSDQLSS FKKKVANQPI YAKPQPRQPA SPTPTAYLNS NDGHSSAASS PGSYSLKKKR  60
   61 SKTSLVYSQP ADSGVGTHYL SQLHYAVEYL KERNEPKTAE EIASYLSTPL TPMLLNLLKK 120
  121 NNRIYYDERN ETFTFKPLHN IRSGAGLLAY LDS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	18.0
Match:	1d8jA
Description:	The central core domain of TFIIE beta
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [154-285]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QKTHVGMSIK ELRDGWPNVT VELEELEKQG EVLLLRTRKD GVPKMVWRND KSCDCHVDKE  60
   61 FQQVWHEIPI PPTLDLASEL GKYGLKPTSV DPSTVKRAGH NQTPKQKKPK TRRGKITNTH 120
  121 LNILRDYSSM KP

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.284	d.54.1	Enolase N-terminal domain-like
View	Download	0.246	d.93.1	SH2 domain
View	Download	0.236	a.95.1	Influenza virus matrix protein M1
View	Download	0.233	a.95.1	Influenza virus matrix protein M1
View	Download	0.226	d.54.1	Enolase N-terminal domain-like
View	Download	0.222	a.121.1	Tetracyclin repressor-like, C-terminal domain
View	Download	0.209	a.36.1	Signal peptide-binding domain
View	Download	0.207	a.36.1	Signal peptide-binding domain

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits