YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC23C11.09
Organism:	Schizosaccharomyces pombe
Length:	959 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC23C11.09.

Description	E-value	Query Range	Subject Range
gi\|75241640, gi\|... - gi\|75241640\|ref\|ZP_00725477.1\| COG0013: Alanyl-tRNA synthetase [Escherichia coli F11], gi\|191171366\|...	1119.0	[0..8]	[957..1]
gi\|227888232, gi... - gi\|227888232\|ref\|ZP_04006037.1\| alanyl-tRNA synthetase [Escherichia coli 83972], gi\|227834501\|gb\|EEJ... SYA_ECOHS - Alanine--tRNA ligase OS=Escherichia coli O9:H4 (strain HS) GN=alaS PE=3 SV=1 gi\|218428383, gi... - gi\|218690819\|ref\|YP_002399031.1\| alanyl-tRNA synthetase [Escherichia coli ED1a], gi\|218428383\|emb\|CA...	1106.0	[0..8]	[957..1]
gi\|75512393, gi\|... - gi\|75512393\|ref\|ZP_00734945.1\| COG0013: Alanyl-tRNA synthetase [Escherichia coli 53638], gi\|18849203... gi\|238901834, gi... - gi\|238901834\|ref\|YP_002927630.1\| alanyl-tRNA synthetase [Escherichia coli BW2952], gi\|238859951\|gb\|A... SYA_ECODH - Alanine--tRNA ligase OS=Escherichia coli (strain K12 / DH10B) GN=alaS PE=3 SV=1 SYA_ECOLI - Alanyl-tRNA synthetase (EC 6.1.1.7) (Alanine--tRNA ligase) (AlaRS) - Escherichia coli gi\|1800083, gi\|8... - gi\|89109484\|ref\|AP_003264.1\| alanyl-tRNA synthetase [Escherichia coli str. K-12 substr. W3110], gi\|1... EG10034 - alanyl-tRNA synthetase / Alanine--tRNA ligase, autorepressor gi\|194422121, gi... - gi\|83585644\|ref\|ZP_00924287.1\| COG0013: Alanyl-tRNA synthetase [Escherichia coli 101-1], gi\|19443900... gi\|226839360, gi... - gi\|254037736\|ref\|ZP_04871794.1\| alanyl t-RNA synthetase [Escherichia sp. 1_1_43], gi\|226839360\|gb\|EE... EG10034 - alanyl-tRNA synthetase / Alanine--tRNA ligase, autorepressor	1106.0	[0..8]	[957..1]
SYA_SHISS - Alanine--tRNA ligase OS=Shigella sonnei (strain Ss046) GN=alaS PE=3 SV=1 gi\|209920136, gi... - gi\|209920136\|ref\|YP_002294220.1\| alanyl-tRNA synthetase [Escherichia coli SE11], gi\|209913395\|dbj\|BA... gi\|75256897, gi\|... - gi\|75256897\|ref\|ZP_00728473.1\| COG0013: Alanyl-tRNA synthetase [Escherichia coli E22], gi\|193065058\|... gi\|193069650, gi... - gi\|75235710\|ref\|ZP_00719884.1\| COG0013: Alanyl-tRNA synthetase [Escherichia coli E110019], gi\|193069... gi\|218555239, gi... - gi\|218555239\|ref\|YP_002388152.1\| alanyl-tRNA synthetase [Escherichia coli IAI1], gi\|218362007\|emb\|CA... gi\|218353020, gi... - gi\|218696288\|ref\|YP_002403955.1\| alanyl-tRNA synthetase [Escherichia coli 55989], gi\|218353020\|emb\|C... gi\|75229772, gi\|... - gi\|75229772\|ref\|ZP_00716302.1\| COG0013: Alanyl-tRNA synthetase [Escherichia coli B7A], gi\|191167095\|... gi\|194427866, gi... - gi\|75210896\|ref\|ZP_00711020.1\| COG0013: Alanyl-tRNA synthetase [Escherichia coli B171], gi\|194427866... SYA_ECO24 - Alanine--tRNA ligase OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=alaS PE=3 SV=1	1106.0	[0..8]	[957..1]
SYA_ECOL5 - Alanine--tRNA ligase OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=alaS PE=3 SV=1	1106.0	[0..8]	[957..1]
gi\|15832808, gi\|... - gi\|15832808\|ref\|NP_311581.1\| alanyl-tRNA synthetase [Escherichia coli O157:H7 str. Sakai], gi\|133630... gi\|168774775, gi... - gi\|187769613\|gb\|EDU33457.1\| alanyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4196], gi\|168774... gi\|189003197, gi... - gi\|189003197\|gb\|EDU72183.1\| alanyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4076], gi\|168778... gi\|189377449, gi... - gi\|189377449\|gb\|EDU95865.1\| alanyl-tRNA synthetase [Escherichia coli O157:H7 str. EC508], gi\|1688002... gi\|25293071 - pir\|\|B91073 alanyl-tRNA synthetase [imported] - Escherichia coli (strain O157:H7, substrain RIMD 050... gi\|195938445 - gi\|195938445\|ref\|ZP_03083827.1\| alanyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4024] gi\|208805868, gi... - gi\|208805868\|ref\|ZP_03248205.1\| alanyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4206], gi\|20... gi\|208735038, gi... - gi\|208813761\|ref\|ZP_03255090.1\| alanyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4045], gi\|20... gi\|208738409, gi... - gi\|208818286\|ref\|ZP_03258606.1\| alanyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4042], gi\|20... gi\|209160191, gi... - gi\|209398791\|ref\|YP_002272160.1\| alanyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4115], gi\|2... gi\|168749982, gi... - gi\|188015823\|gb\|EDU53945.1\| alanyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4113], gi\|168749... gi\|189357241, gi... - gi\|189357241\|gb\|EDU75660.1\| alanyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4401], gi\|168755... gi\|189366853, gi... - gi\|189366853\|gb\|EDU85269.1\| alanyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4501], gi\|168762... SYA_ECO57 - Alanine--tRNA ligase OS=Escherichia coli O157:H7 GN=alaS PE=3 SV=2 gi\|189362083, gi... - gi\|189362083\|gb\|EDU80502.1\| alanyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4486], gi\|168768... gi\|83569947, gi\|... - gi\|83569947\|ref\|ZP_00921395.1\| COG0013: Alanyl-tRNA synthetase [Shigella dysenteriae 1012], gi\|19443... gi\|217327497, gi... - gi\|217327497\|ref\|ZP_03443580.1\| alanyl-tRNA synthetase [Escherichia coli O157:H7 str. TW14588], gi\|2... gi\|254594038, gi... - gi\|254794638\|ref\|YP_003079475.1\| alanyl-tRNA synthetase [Escherichia coli O157:H7 str. TW14359], gi\|...	1105.0	[0..8]	[957..1]
SYA_SHIDS - Alanine--tRNA ligase OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=alaS PE=3 SV=1	1105.0	[0..8]	[957..1]
gi\|218366454, gi... - gi\|218559685\|ref\|YP_002392598.1\| alanyl-tRNA synthetase [Escherichia coli S88], gi\|218366454\|emb\|CAR... SYA_ECOK1 - Alanine--tRNA ligase OS=Escherichia coli O1:K1 / APEC GN=alaS PE=3 SV=1 gi\|237706683, gi... - gi\|237706683\|ref\|ZP_04537164.1\| alanyl-tRNA synthetase [Escherichia sp. 3_2_53FAA], gi\|226899723\|gb\|... SYA_ECOUT - Alanine--tRNA ligase OS=Escherichia coli (strain UTI89 / UPEC) GN=alaS PE=3 SV=1	1105.0	[0..8]	[957..1]
gi\|56480163, gi\|... - gi\|56480163\|ref\|NP_708505.2\| alanyl-tRNA synthetase [Shigella flexneri 2a str. 301], gi\|56383714\|gb\|... SYA_SHIF8 - Alanine--tRNA ligase OS=Shigella flexneri serotype 5b (strain 8401) GN=alaS PE=3 SV=1 SYA_SHIFL - Alanine--tRNA ligase OS=Shigella flexneri GN=alaS PE=3 SV=1 gi\|30064057, gi\|... - gi\|30064057\|ref\|NP_838228.1\| alanyl-tRNA synthetase [Shigella flexneri 2a str. 2457T], gi\|30042313\|g...	1104.0	[0..8]	[957..1]
SYA_SHIB3 - Alanine--tRNA ligase OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=alaS PE=3 SV=1	1104.0	[0..8]	[957..1]

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Predicted Domain #1

Region A:
Residues: [1-500]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTAESEVVNW PANEIRRTFL KYFEDHGHTI VPSSSVIPYD DPTLLFANAG MNQFKPIFLG  60
   61 TVDPSSDFAK LKRACDSQKC IRAGGKHNDL EDVGKDNYHH TMFEMLGNWS FGDYFKKEAI 120
  121 AMAWDLLTNV YGLKKDQLYV TYFGGHEESG LEPDLEARQL WLDIGIDESR VIPGSLKDNF 180
  181 WEMGDQGPCG PCSEIHYDRI GNRTVPELVN MDDPNVLEIW NIVFIQFNRE KDGSLRPLPN 240
  241 RHVDTGMGFE RLVSVIQNKT SNYDTDVFSP IFAKIQELTN ARPYTGKMGD EDVDGIDTAY 300
  301 RVVADHVRTL TFAISDGGVP NNEGRGYVLR RILRRGARYV RKKFGVPIGN FFSRLSLTVV 360
  361 EQMGDFFPEL KRKVDDVREL LDEEEESFSR TLDRGEKMFE QYAAAAKKTP SKTLQGNDVW 420
  421 RLYETYGFPV DLTHLMAEEA GIKIDEPGFE AAQARSKEIS KQASKGGSSG DDLLVLDVHA 480
  481 LGALSKMDDI PETDDVFKHN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	1riqA
Description:	The crystal structure of the catalytic fragment of the alanyl-tRNA synthetase
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [501-862]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SVSLKSVIKG IYHKGGFQKS TEGFNSGEQL GLLLDRTNFY AEQGGQEYDT GHIVIDGVAD  60
   61 FRVTNVQVYA GYVLHTGFLE YGNLTVNDSV VCEYDEIRRW HLMNNHTVTH ILNLALRNTL 120
  121 GDGIDQRGSL VSQEKLRFDF SYKSSIPIDK LLLVENYCNN VIQDNLSVYS KEVALSKAKE 180
  181 INGLRAVFGE VYPDPVRVVC IGVDIDTLLQ EPKKPDWTKY SIEFCGGTHC DKSGEIKDFV 240
  241 ILEENGIAKG IRRIVAVTST EANRVSRLAN EFDARIAKLE KMPFSPAKEA ELKKISVDLS 300
  301 KLVVAAVRKH AMKERIAKIT KQVQEHVKAI NAAEQKEVVN VVTEYFKENP DMSFVVAKVP 360
  361 IS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	61.221849
Match:	1qf6A
Description:	Threonyl-tRNA synthetase (ThrRS), C-terminal domain; Threonyl-tRNA synthetase (ThrRS), N-terminal 'additional' domain; Threonyl-tRNA synthetase (ThrRS), second 'additional' domain; Threonyl-tRNA synthetase (ThrRS)
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [863-959]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ANPKALSFAL TYAKKNLKDK SIYLLASDDT KVAHACLVSP EAMKKLTPQE WSQKVCHSIG  60
   61 GRSGGKGDTC QGVGDKPLSI DVAVEEAIEF FQGKLTI

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	8.744727
Match:	PF02272.10
Description:	No description for PF02272.10 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.808	N/A	N/A	d.52.9	Description not found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits