YRC Public Data Repository - Protein Structure Prediction

Protein:	rad4
Organism:	Schizosaccharomyces pombe
Length:	648 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rad4.

Description	E-value	Query Range	Subject Range
gi\|32418768, gi\|... - gi\|32418768\|ref\|XP_329862.1\| hypothetical protein [Neurospora crassa], gi\|28919794\|gb\|EAA29196.1\| hy... gi\|85090470 - gi\|85090470\|ref\|XP_958432.1\| hypothetical protein [Neurospora crassa OR74A]	326.0	[0..4]	[643..24]
gi\|37359872 - gi\|37359872\|dbj\|BAC97914.1\| mKIAA0259 protein [Mus musculus]	286.0	[0..91]	[643..401]
gi\|109483894, gi... - gi\|109485305\|ref\|XP_001072207.1\| PREDICTED: similar to topoisomerase (DNA) II beta binding protein [...	284.0	[0..91]	[643..425]
gi\|46111691, gi\|... - gi\|46111691\|ref\|XP_382903.1\| hypothetical protein FG02727.1 [Gibberella zeae PH-1], gi\|42546608\|gb\|E...	282.0	[0..4]	[647..17]
gi\|39940400, gi\|... - gi\|39940400\|ref\|XP_359737.1\| hypothetical protein MGG_05040 [Magnaporthe grisea 70-15], gb\|EAA52348....	276.0	[0..3]	[646..17]
gi\|90298535, gi\|... - gi\|90298535\|gb\|EAS28166.1\| hypothetical protein CIMG_09370 [Coccidioides immitis RS], gi\|119174843\|r...	268.0	[0..3]	[612..726]
gi\|49102138, gi\|... - gi\|67541452\|ref\|XP_664500.1\| hypothetical protein AN6896.2 [Aspergillus nidulans FGSC A4], ref\|XP_41...	268.0	[0..3]	[622..18]
TOB1B_XENLA - DNA topoisomerase 2-binding protein 1-B OS=Xenopus laevis GN=topbp1-B PE=2 SV=1	267.0	[0..96]	[643..353]

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Predicted Domain #1

Region A:
Residues: [1-86]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSSKPLKGF VICCTSIDLK QRTEISTKAT KLGAAYRSDF TKDVTHLIAG DFDTPKYKFA  60
   61 AKSRPDIKIM SSEWIPVLYE SWVQGE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	39.522879
Match:	2owoA
Description:	No description for 2owoA was found.

Predicted Domain #2

Region A:
Residues: [87-384]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DLDDGLLVDK HFLPTLFKCR VCLTNIGQPE RSRIENYVLK HGGTFCPDLT RDVTHLIAGT  60
   61 SSGRKYEYAL KWKINVVCVE WLWQSIQRNA VLEPQYFQLD MPAEKIGLGA YVRLDPNTTE 120
  121 AKSYSENQKI SKNKEKSGQS LAALAEEADL EPVIMKRGKK RDRSILWEEL NNGKFEFSSR 180
  181 SEENSVLLDD FTPETVQPLE ENELDTELNI ENEAKLFKNL TFYLYEFPNT KVSRLHKCLS 240
  241 DNGGQISEFL SSTIDFVVIP HYFPVDELPI FSFPTVNEWW IERCLYYKKI FGIDEHAL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	12.69897
Match:	1z56C
Description:	Co-Crystal Structure of Lif1p-Lig4p
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [385-491]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AKPFFRPSLV PYFNGLSIHL TGFKGEELSH LKKALTILGA VVHEFLGVQR SILLVNTNEP  60
   61 FSMKTRFKIQ HATEWNVRVV GVAWLWNIIQ SGKFIDQVSP WAIDKKE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	31.30103
Match:	1jnxX
Description:	Breast cancer associated protein, BRCA1
Matching Structure (courtesy of the PDB):

Predicted Domain #4

Region A:
Residues: [492-648]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NQEIKKFTNQ NNMVFPTSDR DTRLQNSLAQ QPIGHSTPHN SPSLLSVKKR QNNHIRSNTL  60
   61 IQLNSNSKDS TIFPRRSVTV PGDKIDTVWK SSVTKPETPT SPQEHVSYID PDAQREKHKL 120
  121 YAQLTSNVDA IPPANDLQNQ ENGLLLITES HRKLRRR

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits