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View Structure Prediction Details

Protein: rad32
Organism: Schizosaccharomyces pombe
Length: 649 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rad32.

Description E-value Query
Range
Subject
Range
MRE11_MOUSE - Double-strand break repair protein MRE11A OS=Mus musculus GN=Mre11a PE=1 SV=1
602.0 [0..2] [647..3]
MRE11_RAT - Double-strand break repair protein MRE11A OS=Rattus norvegicus GN=Mre11a PE=1 SV=1
589.0 [0..2] [631..3]
gi|114639862, gi... - gi|114639862|ref|XP_001142422.1| PREDICTED: meiotic recombination 11 homolog A isoform 4 [Pan troglo...
588.0 [0..7] [646..2]
MRE11A - MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
588.0 [0..7] [646..2]
gi|73987751 - gi|73987751|ref|XP_542244.2| PREDICTED: similar to Double-strand break repair protein MRE11A (MRE11 ...
584.0 [0..12] [646..7]
MRE11_XENLA - Double-strand break repair protein MRE11 OS=Xenopus laevis GN=mre11 PE=2 SV=1
581.0 [0..12] [632..8]
MRE11_MACFA - Double-strand break repair protein MRE11A OS=Macaca fascicularis GN=MRE11A PE=2 SV=1
579.0 [0..7] [631..2]

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Predicted Domain #1
Region A:
Residues: [1-350]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPNDPSDMNN ELHNENTIRI LISSDPHVGY GEKDPVRGND SFVSFNEILE IARERDVDMI  60
   61 LLGGDIFHDN KPSRKALYQA LRSLRLNCLG DKPCELELLS DTSLTTGDTA VCNINYLDPN 120
  121 INVAIPVFSI HGNHDDPSGD GRYSALDILQ VTGLVNYFGR VPENDNIVVS PILLQKGFTK 180
  181 LALYGISNVR DERLYHSFRE NKVKFLRPDL YRDEWFNLLT VHQNHSAHTP TSYLPESFIQ 240
  241 DFYDFVLWGH EHECLIDGSY NPTQKFTVVQ PGSTIATSLS PGETAPKHCG ILNITGKDFH 300
  301 LEKIRLRTVR PFIMKDIILS EVSSIPPMVE NKKEVLTYLI SKVEEAITEA 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 44.69897
Match: 1ii7A
Description: Mre11
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity 3.13006743434485 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 2.78838275355792 bayes_pls_golite062009
protein serine/threonine phosphatase activity 1.72108778738758 bayes_pls_golite062009
binding 1.44538582463569 bayes_pls_golite062009
catalytic activity 1.39852585255405 bayes_pls_golite062009
phosphoprotein phosphatase activity 1.23036240099336 bayes_pls_golite062009
phosphoric ester hydrolase activity 0.899406797746366 bayes_pls_golite062009
phosphatase activity 0.76188635342041 bayes_pls_golite062009
transporter activity 0.31687928484091 bayes_pls_golite062009
protein binding 0.283905381578004 bayes_pls_golite062009
calcium-dependent protein serine/threonine phosphatase activity 0.0429959933934001 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [351-474]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NAQWYEAQGT VPVVENEKPP LPLIRLRVDY TGGYQTENPQ RFSNRFVGRV ANATDVVQFY  60
   61 LKKKYTRSKR NDGLYTSAVE DIKINSLRVE SLVNEYLKTN RLECLPEDSL GEAVVNFVEK 120
  121 DDRD

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 18.267606
Match: PF04152.5
Description: No description for PF04152.5 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [475-649]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AIKECVETQL NKQINLLVKK RVTEENLEQE ISSIINDLPK ISTTKRKDYE ELPEEVSETS  60
   61 INIAEHTPVL KHTSSLLDHH SPLATSSSEH EMEATPSPAL LKKTNKRREL PSSLTKKNTR 120
  121 TPQRSKEVKK VPARKLSQST KKSDKNTQST LLFYDPSSTT EAQYLDNEDD EILDD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle