YRC Public Data Repository - Protein Structure Prediction

Protein:	ptb1
Organism:	Schizosaccharomyces pombe
Length:	311 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ptb1.

Description	E-value	Query Range	Subject Range
gi\|208967224 - gi\|208967224\|dbj\|BAG73626.1\| Rab geranylgeranyltransferase beta subunit [synthetic construct] ENSPTRT00000001654 - null RABGGTB - Rab geranylgeranyltransferase, beta subunit gi\|109008511 - gi\|109008511\|ref\|XP_001101556.1\| PREDICTED: similar to Rab geranylgeranyltransferase, beta subunit [...	386.0	[0..2]	[311..16]
gi\|73960159 - gi\|73960159\|ref\|XP_855504.1\| PREDICTED: similar to Rab geranylgeranyltransferase, beta subunit [Cani...	385.0	[0..2]	[311..171]
gi\|148679950, gi... - gi\|74227618\|dbj\|BAE35665.1\| unnamed protein product [Mus musculus], gi\|254553293\|ref\|NP_001156950.1\|...	383.0	[0..2]	[311..16]
gi\|149026283, gi... - gi\|51261120\|gb\|AAH78683.1\| Rab geranylgeranyltransferase, beta subunit [Rattus norvegicus], gi\|14902...	383.0	[0..2]	[311..16]
gi\|66911331, gi\|... - gi\|76253908\|ref\|NP_998277.2\| RAB geranylgeranyltransferase, beta subunit [Danio rerio], gi\|66911331\|...	383.0	[0..2]	[311..16]
gi\|50751774 - gi\|50751774\|ref\|XP_422548.1\| PREDICTED: similar to Rab geranylgeranyltransferase, beta subunit [Gall...	382.0	[0..3]	[311..135]

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Predicted Domain #1

Region A:
Residues: [1-311]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVLLRDKHI SYLHDIGNRT DELDFWLKEH LHVSAIYWSC MSFWLLKKKD QIDKERIVSF  60
   61 LLSCLTESGG FACYPGHDDH ITNTVYAVQV LAMLDSLHVV DKDKVASYII GLQNEDGSMK 120
  121 GDRWGEIDAR FLYSGINCLA ILGKLDYLNK NTAVDWLMKC YNFDGGFGLC PGAESHGAMV 180
  181 FTCVAALKIL NKLDLIDEEL LGWWISERQV KGGGLNGRPE KLPDSCYGWW DLSPLAIIGK 240
  241 LDWIDRNQLI DFLLGTQDAD SGGFADRKED ATDVYHTCFS LAGLSLLQFP NIEPVDPRFC 300
  301 LPLEVTQKMK L

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	107.0
Match:	1dceB
Description:	Rab geranylgeranyltransferase, beta subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protein prenyltransferase activity	13.7736019666673	bayes_pls_golite062009
protein geranylgeranyltransferase activity	12.9757276506747	bayes_pls_golite062009
Rab geranylgeranyltransferase activity	12.8088011327065	bayes_pls_golite062009
prenyltransferase activity	11.6786310564018	bayes_pls_golite062009
protein farnesyltransferase activity	4.15546866363415	bayes_pls_golite062009
CAAX-protein geranylgeranyltransferase activity	3.9191671794027	bayes_pls_golite062009
transferase activity	1.0950430724883	bayes_pls_golite062009
binding	1.09280744446864	bayes_pls_golite062009
catalytic activity	0.497699107100544	bayes_pls_golite062009
protein binding	0.427029962299636	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: