YRC Public Data Repository - Protein Structure Prediction

Protein:	SPCC330.06c
Organism:	Schizosaccharomyces pombe
Length:	156 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPCC330.06c.

Description	E-value	Query Range	Subject Range
gi\|21912927 - gi\|21912927\|emb\|CAC84143.2\| thioredoxin peroxidase [Nicotiana tabacum]	154.0	[0..1]	[156..77]
gi\|51892064, gi\|... - gi\|51892064\|ref\|YP_074755.1\| 2-cys peroxiredoxin [Symbiobacterium thermophilum IAM 14863], gi\|518557...	153.0	[0..1]	[156..1]
gi\|157886060, gi... - gi\|50539996\|ref\|NP_001002468.1\| peroxiredoxin 2 [Danio rerio], gi\|49900827\|gb\|AAH76347.1\| Peroxiredo...	153.0	[0..3]	[155..7]
gi\|62901916 - gi\|62901916\|gb\|AAY18909.1\| thioredoxin peroxidase 1-like [synthetic construct]	151.0	[0..3]	[155..31]
gi\|109123569 - gi\|109123569\|ref\|XP_001108992.1\| PREDICTED: peroxiredoxin 2 isoform 1 [Macaca mulatta]	151.0	[0..3]	[155..7]
gi\|17232133, gi\|... - gi\|17232133\|ref\|NP_488681.1\| peroxiredoxin [Nostoc sp. PCC 7120], gi\|17133778\|dbj\|BAB76340.1\| peroxi... gi\|75701970, gi\|... - gi\|75908245\|ref\|YP_322541.1\| Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen... gi\|25285298 - pir\|\|AI2385 peroxiredoxin [imported] - Nostoc sp. (strain PCC 7120)	151.0	[0..2]	[156..11]
gi\|33865747, gi\|... - gi\|33865747\|ref\|NP_897306.1\| thioredoxin peroxidase [Synechococcus sp. WH 8102], gi\|33632917\|emb\|CAE...	151.0	[0..2]	[155..7]
PRDX2_CRIGR - Peroxiredoxin-2 OS=Cricetulus griseus GN=PRDX2 PE=2 SV=3	151.0	[0..4]	[155..8]
gi\|3193232 - gi\|3193232\|gb\|AAC77922.1\| peroxidoxin-2 [Onchocerca ochengi]	151.0	[0..4]	[155..10]
gi\|78184723, gi\|... - gi\|78184723\|ref\|YP_377158.1\| thioredoxin peroxidase [Synechococcus sp. CC9902], gi\|78169017\|gb\|ABB26...	151.0	[0..2]	[155..10]

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Predicted Domain #1

Region A:
Residues: [1-156]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVAVGSTLPK VTLWENKPEE VVEFPSQGKF IIVGVPGAFT PPCSSQVPGY IANEKQFAAK  60
   61 GISGIYVVAV NDVFVTKAWK KSFDGGEQSG VHFVADWNGE FTKAFDAGFD ASGLLGPLRS 120
  121 KRYAAVVENG KVVKVFIENE VTDVDISSAD KVLSSL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	37.045757
Match:	1qmvA
Description:	Thioredoxin peroxidase 2 (thioredoxin peroxidase B, 2-cys peroxiredoxin)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
antioxidant activity	3.66884588063322	bayes_pls_golite062009
peroxidase activity	3.43831566988273	bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor	3.43831566988273	bayes_pls_golite062009
glutathione peroxidase activity	2.56524997297011	bayes_pls_golite062009
peroxiredoxin activity	2.12777217096121	bayes_pls_golite062009
thioredoxin peroxidase activity	1.96134566495756	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	1.8187537496904	bayes_pls_golite062009
protein disulfide oxidoreductase activity	1.47769936616412	bayes_pls_golite062009
disulfide oxidoreductase activity	1.32811008894503	bayes_pls_golite062009
binding	1.25802922431343	bayes_pls_golite062009
selenium binding	1.1082524159827	bayes_pls_golite062009
catalytic activity	0.672192331361968	bayes_pls_golite062009
transcription regulator activity	0.52671047749426	bayes_pls_golite062009
protein binding	0.134341907247724	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: