YRC Public Data Repository - Protein Structure Prediction

Protein:	ppp1
Organism:	Schizosaccharomyces pombe
Length:	607 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ppp1.

Description	E-value	Query Range	Subject Range
gi\|114685878 - gi\|114685878\|ref\|XP_515076.2\| PREDICTED: pescadillo homolog 1, containing BRCT domain isoform 3 [Pan...	614.0	[0..5]	[586..6]
PESC_RAT - Pescadillo homolog OS=Rattus norvegicus GN=Pes1 PE=2 SV=1	609.0	[0..5]	[605..6]
gi\|55715986 - gb\|AAH86254.1\| Unknown (protein for MGC:98773) [Xenopus laevis] PESC_MOUSE - Pescadillo homolog OS=Mus musculus GN=Pes1 PE=1 SV=1	609.0	[0..5]	[605..6]
PESC_XENLA - Pescadillo homolog OS=Xenopus laevis GN=pes1 PE=2 SV=1	601.0	[0..5]	[602..6]
gi\|45361665, gi\|... - gi\|45361665\|ref\|NP_989410.1\| pescadillo homolog 1, containing BRCT domain [Xenopus (Silurana) tropic...	598.0	[0..5]	[602..6]
gi\|55729117\|emb\|... - hypothetical protein [Pongo pygmaeus] gi\|55729117 - gi\|55729117\|emb\|CAH91295.1\| hypothetical protein [Pongo abelii]	596.0	[0..5]	[477..6]
gi\|73995433 - gi\|73995433\|ref\|XP_543480.2\| PREDICTED: similar to pescadillo homolog 1, containing BRCT domain [Can...	594.0	[0..5]	[602..6]

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Predicted Domain #1

Region A:
Residues: [1-193]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MARVKQKGKA GAARIYITRN QALKKLQLTL ADFRRICILK GVYPREPKNK KKANKGSTAP  60
   61 VTFYYTKDIQ YLLHEPIVQK FREYKVFARK LSKALGKGEL ETAKRLEARK PTYSLDHIIK 120
  121 ERYPTFHDAL KDIDDALSML FLFSTMPVTD KIGAATVANC ERLCAEFQHY VIRSNSLRKA 180
  181 FLSIKGIYYQ AEI

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [194-272]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FGEQITWIVP YKFAQSVPTD VDFRIMHTFL EFYQALMGFV NFKLYNTLGL RYPPKIDVAK  60
   61 SESAAGLAAY ELEESSSLP

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [273-607]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AIVHGNNKNA RKNIATLKSK IRDIVNSDAN VVEQSEKTTE DADEEPETEE NLDEFKPADG  60
   61 ADNEDSKSLV SHISSSNTSL FSNFTFFLSR EVPRFSLEFV IRAFGGKVGW DPILGSGSPF 120
  121 SESDPVITHH ICDRPHISQK YEGRIYIQPQ WVYDSINKGI LERTDLYACG ATLPPHLSPF 180
  181 VKVGENDYDP EAELSAEEND DVSEALDDNI SGEAVPISKK NDEPENVEQI DDAEEEDLEH 240
  241 QRELEAEAGG VAYSEYVKQN SKSAKKTKKR QRDTLTAEEK EEKEAKELSK MMMSNKQRKL 300
  301 YSKLKNENSK NENYNNALRN RKRDIEKRKK LKVEN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	7.045757
Match:	1i84S
Description:	Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits