YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC5H10.09c
Organism:	Schizosaccharomyces pombe
Length:	267 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC5H10.09c.

Description	E-value	Query Range	Subject Range
gi\|27262460 - gi\|27262460\|gb\|AAN87511.1\| 3-methyl-2-oxobutanoate hydroxymethyltransferase [Heliobacillus mobilis]	425.0	[0..4]	[266..3]
SO0870 - 3-methyl-2-oxobutanoate hydroxymethyltransferase PANB_SHEON - 3-methyl-2-oxobutanoate hydroxymethyltransferase OS=Shewanella oneidensis (strain MR-1) GN=panB PE=3...	424.0	[0..3]	[266..1]
gi\|85859368, gi\|... - gi\|85859368\|ref\|YP_461570.1\| 3-methyl-2-oxobutanoate hydroxymethyltransferase [Syntrophus aciditroph...	424.0	[0..4]	[266..14]
gi\|21957513, gi\|... - gi\|22124699\|ref\|NP_668122.1\| 3-methyl-2-oxobutanoate hydroxymethyltransferase [Yersinia pestis KIM],...	423.0	[0..2]	[267..22]
gi\|126175691, gi... - gi\|68543346\|ref\|ZP_00583054.1\| Ketopantoate hydroxymethyltransferase [Shewanella baltica OS155], gi\|... gi\|113948900, gi... - gi\|160874001\|ref\|YP_001553317.1\| 3-methyl-2-oxobutanoate hydroxymethyltransferase [Shewanella baltic... gi\|151363999, gi... - gi\|152999381\|ref\|YP_001365062.1\| 3-methyl-2-oxobutanoate hydroxymethyltransferase [Shewanella baltic... gi\|149116833, gi... - gi\|217972058\|ref\|YP_002356809.1\| 3-methyl-2-oxobutanoate hydroxymethyltransferase [Shewanella baltic...	423.0	[0..3]	[266..1]
PANB_SHESM - 3-methyl-2-oxobutanoate hydroxymethyltransferase OS=Shewanella sp. (strain MR-4) GN=panB PE=3 SV=1	423.0	[0..3]	[266..1]
PANB_SHESR - 3-methyl-2-oxobutanoate hydroxymethyltransferase OS=Shewanella sp. (strain MR-7) GN=panB PE=3 SV=1	423.0	[0..3]	[266..1]
gi\|68515580, gi\|... - gi\|68546769\|ref\|ZP_00586314.1\| Ketopantoate hydroxymethyltransferase [Shewanella amazonensis SB2B], ...	423.0	[0..3]	[266..16]
gi\|88926139, gi\|... - gi\|88944133\|ref\|ZP_01147466.1\| Ketopantoate hydroxymethyltransferase [Desulfotomaculum reducens MI-1...	422.0	[0..4]	[266..3]
gi\|84360926, gi\|... - gi\|84360926\|ref\|ZP_00985613.1\| COG0413: Ketopantoate hydroxymethyltransferase [Burkholderia dolosa A...	422.0	[0..2]	[266..8]

Back

Predicted Domain #1

Region A:
Residues: [1-267]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLKQITIST LRQWKLANKK FACITAYDAS FSRLFAEQGM PVMLVGDSLG MTAQGHSTTL  60
   61 PVSVEDIAYH TKSVRRGAPN RLLMADLPFM SYSTWEDACK NAATVMRAGA NIVKIEGGGN 120
  121 WIFEIVQRLT ERSVPVAGHL GLTPQSVNIF GGYKIQGREQ SAAARLIENA QQLEKFGAQL 180
  181 LVLECIPESL AEQITKTISI PTIGIGAGKH TDGQILVMHD ALGITGGRPP KFAKNFLSGA 240
  241 GDIRTAIQRY IYEVEQGLYP AEEHSFQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	117.0
Match:	1m3uA
Description:	Ketopantoate hydroxymethyltransferase PanB
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
3-methyl-2-oxobutanoate hydroxymethyltransferase activity	4.08693637310631	bayes_pls_golite062009
catalytic activity	2.59838799615646	bayes_pls_golite062009
hydroxymethyl-, formyl- and related transferase activity	2.05689968523792	bayes_pls_golite062009
transferase activity	1.07154136609184	bayes_pls_golite062009
glycine hydroxymethyltransferase activity	0.646649320021871	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.366715189574293	bayes_pls_golite062009
oxo-acid-lyase activity	0.0960362356555544	bayes_pls_golite062009
carbon-carbon lyase activity	0.0846611486307003	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: