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View Structure Prediction Details

Protein: ndk1
Organism: Schizosaccharomyces pombe
Length: 151 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ndk1.

Description E-value Query
Range
Subject
Range
gi|79160090, gi|... - gi|79160090|gb|AAI07895.1| NME1-NME2 protein [Homo sapiens], gi|119614969|gb|EAW94563.1| hCG2001850,...
279.0 [0..2] [151..143]
gi|61372303, gi|... - gi|61372303|gb|AAX43820.1| non-metastatic cells 2 [synthetic construct], gi|61372297|gb|AAX43819.1| ...
275.0 [0..2] [151..3]
NDKB_RAT - Nucleoside diphosphate kinase B OS=Rattus norvegicus GN=Nme2 PE=1 SV=1
275.0 [0..2] [151..3]
NDKB_PONAB - Nucleoside diphosphate kinase B OS=Pongo abelii GN=NME2 PE=2 SV=1
NDKB_PONPY - Nucleoside diphosphate kinase B - Pongo pygmaeus (Orangutan)
274.0 [0..2] [151..3]
NDKB_MOUSE - Nucleoside diphosphate kinase B OS=Mus musculus GN=Nme2 PE=1 SV=1
273.0 [0..2] [151..3]

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Predicted Domain #1
Region A:
Residues: [1-151]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTEQTFIAV KPDAVQRGLI GYIISKFELK GYKLRALKFL VPSRDLVEEH YAEHKGKPFY  60
   61 EKLVGFMASG PVCAMIWEGK QAVKTGRLML GASNPLDSAP GTIRGDYGID LGRNVCHGSD 120
  121 SIESANREIK LWFQPSEIQV YDRTIEPWIY E

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 74.69897
Match: 1nueA
Description: Nucleoside diphosphate kinases
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleobase, nucleoside, nucleotide kinase activity 9.54806938681864 bayes_pls_golite062009
phosphotransferase activity, phosphate group as acceptor 8.99343206813136 bayes_pls_golite062009
nucleoside diphosphate kinase activity 6.31603417387406 bayes_pls_golite062009
kinase activity 5.17632668597727 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 4.81683227683584 bayes_pls_golite062009
tubulin binding 3.91203457981165 bayes_pls_golite062009
transferase activity 3.88584335567051 bayes_pls_golite062009
microtubule binding 3.30486676956703 bayes_pls_golite062009
cytoskeletal protein binding 2.90440302787538 bayes_pls_golite062009
transcription regulator activity 2.33936391947568 bayes_pls_golite062009
nucleic acid binding 2.14345344254908 bayes_pls_golite062009
DNA binding 1.9929237581784 bayes_pls_golite062009
binding 1.77213317402453 bayes_pls_golite062009
catalytic activity 1.54275558650196 bayes_pls_golite062009
protein binding 1.44203715518441 bayes_pls_golite062009
transcription factor activity 1.25823661686679 bayes_pls_golite062009
gamma-tubulin binding 0.715852577944201 bayes_pls_golite062009
ATP binding 0.642661537717629 bayes_pls_golite062009
adenyl ribonucleotide binding 0.611368256550302 bayes_pls_golite062009
adenyl nucleotide binding 0.594323192037838 bayes_pls_golite062009
ribonucleotide binding 0.548739243763112 bayes_pls_golite062009
purine ribonucleotide binding 0.548674300422543 bayes_pls_golite062009
purine nucleotide binding 0.538092730319695 bayes_pls_golite062009
nucleotide binding 0.532504383462049 bayes_pls_golite062009

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