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View Structure Prediction Details

Protein: mac1
Organism: Schizosaccharomyces pombe
Length: 756 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mac1.

Description E-value Query
Range
Subject
Range
NIPBL - Nipped-B homolog (Drosophila)
268.0 [0..173] [756..251]
gi|114600545, gi... - gi|114600547|ref|XP_001146090.1| PREDICTED: delangin isoform 3 [Pan troglodytes], gi|114600545|ref|X...
266.0 [0..173] [756..251]
gi|109077003 - gi|109077003|ref|XP_001096346.1| PREDICTED: similar to delangin isoform A isoform 2 [Macaca mulatta]
259.0 [0..173] [756..140]
gi|44983522, gi|... - gi|45190580|ref|NP_984834.1| AEL027Wp [Ashbya gossypii ATCC 10895], gi|44983522|gb|AAS52658.1| AEL02...
gi|44983522 - gi|44983522|gb|AAS52658.1| AEL027Wp [Ashbya gossypii ATCC 10895]
256.0 [0..3] [647..4]
gi|94368817 - gi|94368817|ref|XP_996982.1| PREDICTED: similar to Ribosome-binding protein 1 (Ribosome receptor pro...
253.0 [0..154] [751..201]

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Predicted Domain #1
Region A:
Residues: [1-283]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIRNTLAFLA ILFLLIPTAL LIIGSVSVPS TRMTLAKVEG TEFGIFGTCT GNGTDCTETS  60
   61 FGYNASSSLI DDFYYKGDKR LVLSKVLITH IISAFLSFLS AIFVFFSIFL VNQAVNIINI 120
  121 IVVFITTLLT CLAFAIELVL FLPHNTWQSY VTAGAIGSDL IAILALCLRS VSISRIGQKS 180
  181 ARLEHVDTMN SSYSSYKTDV KYPLALDDKL SSVPTLPKFH DALTSTSEFG PPSDSGDTVG 240
  241 TTQYPGDIKY ATGYESTVAS PVPSRVAKLS SRDTPSIIAD YDE

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.06
Match: 1xioA
Description: Anabaena sensory rhodopsin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
receptor activity 3.58361836489063 bayes_pls_golite062009
transmembrane receptor activity 3.33630997080952 bayes_pls_golite062009
signal transducer activity 3.11942296016938 bayes_pls_golite062009
molecular transducer activity 3.11942296016938 bayes_pls_golite062009
G-protein coupled receptor activity 2.95733170421117 bayes_pls_golite062009
peptide receptor activity 1.1212930259621 bayes_pls_golite062009
peptide receptor activity, G-protein coupled 1.10830486743897 bayes_pls_golite062009
binding 0.926116249600475 bayes_pls_golite062009
peptide binding 0.889667813639602 bayes_pls_golite062009
neurotransmitter binding 0.757435102903059 bayes_pls_golite062009
neurotransmitter receptor activity 0.720585549720668 bayes_pls_golite062009
neuropeptide receptor activity 0.069783659085636 bayes_pls_golite062009
neuropeptide binding 0.069783659085636 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [284-346]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FRKSESSPSR SSVLSTSKPE VHETEGYCPH KTGNRPGFPS LNIPRTRPTT AGIANTQFDL  60
   61 EPY

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [347-511]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RNRQAGSISS EGTDSRFFDV ENQVSVAQTP SVKPEMFPKT ARPFAAIHAN ASSTQLRNTE  60
   61 NITHPGIPNH FAKTTSSVFD EPPATRMPQT RSPVNDHSSF PSDLPIKGEM STNMTGAPRV 120
  121 GSRNNSSNDL HAQAGMLKNV GNGPRNAPRN NSSNNLHAQG GMPMN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [512-756]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRGPRGAPRN NSSGDLHIQS GMPMNGRNGP RDTSRNNSSS DLYAQSGMHP NMNNGHRGAP  60
   61 RNNSSNDLHA HGGMPVNMRG PRNTSRNNSS SEFNAQIPMN LRNGPRNASR SNSSTDLFGQ 120
  121 SGIPGNSRGM PTSPNSRNNS ALDLSMHGIP LANNSRQFKR PSYGNMSRPS FELNGSRNPS 180
  181 HGSLNTAHAG MGYGPRSMMR DPQNLSNVPP VSNTLDQLSG NADFELPVRG NRNNRRGPGG 240
  241 NRMIR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


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