YRC Public Data Repository - Protein Structure Prediction

Protein:	hal4
Organism:	Schizosaccharomyces pombe
Length:	636 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for hal4.

Description	E-value	Query Range	Subject Range
tr\|M3W6V8\|M3W6V8... - Tyrosine-protein kinase OS=Felis catus GN=SRC PE=3 SV=1 gi\|73991940 - gi\|73991940\|ref\|XP_865870.1\| PREDICTED: similar to Proto-oncogene tyrosine-protein kinase Src (p60-S...	303.0	[0..88]	[633..3]
gi\|190690677, gi... - gi\|190690677\|gb\|ACE87113.1\| v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) protei... SRC - v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	302.0	[0..88]	[633..3]
gi\|60654299 - gi\|60654299\|gb\|AAX29840.1\| v-src sarcoma viral oncogene-like [synthetic construct]	302.0	[0..88]	[633..3]
gi\|109092120, gi... - gi\|109092122\|ref\|XP_001092301.1\| PREDICTED: proto-oncogene tyrosine-protein kinase SRC isoform 2 [Ma...	301.0	[0..88]	[633..3]
gi\|61504 - gi\|61504\|emb\|CAA24496.1\| protein p90gag-yes [Avian sarcoma virus] gi\|61504, gi\|9626157 - ref\|NP_040506.1\| p30 gag-yes protein [Y73 sarcoma virus], gi\|61504\|emb\|CAA24496.1\| p90gag-yes protei...	301.0	[0..10]	[635..200]
SRC_AVIST - Tyrosine-protein kinase transforming protein Src OS=Avian sarcoma virus (strain S2) GN=V-SRC PE=3 SV...	301.0	[0..89]	[617..2]
gi\|3003004 - gi\|3003004\|gb\|AAC08990.1\| src tyrosine kinase [Rous sarcoma virus - Schmidt-Ruppin B] gi\|3003004 - gi\|3003004\|gb\|AAC08990.1\| src tyrosine kinase [Rous sarcoma virus - Schmidt-Ruppin B]	301.0	[0..89]	[617..2]
gi\|223627 - gi\|223627\|prf\|\|0903255A protein v-src	301.0	[0..87]	[617..246]
gi\|223452 - gi\|223452\|prf\|\|0806225A genome Y73	301.0	[0..10]	[635..200]
SRC_RAT - Proto-oncogene tyrosine-protein kinase Src OS=Rattus norvegicus GN=Src PE=1 SV=3	301.0	[0..88]	[617..3]

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Predicted Domain #1

Region A:
Residues: [1-216]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGEKDKLHEI SSKFASLGLG SLKSTPKARE TTEPPPPSSQ QPPSTPNGKE AASPSALKQN  60
   61 VRPSLNSVQQ TPASIDAVAS SSNVSLQSQQ PLSKPVVSSK PNQTTAMPPP SNNPSRHVSS 120
  121 TSNKPAAVSP NPAAHHAELP SGSVPPSASV SRANSTATTT PHKAGVVSNP AAANVHVLSV 180
  181 AASPNPSTPS NGPAPVSTTA TPSRNPVTRL QRIFSQ

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [217-345]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSVSRQNSRT GRGAAVANTE ETNSTGGSET GGAANSSSTS NPSSAKWSRF TVYDDASHTH  60
   61 QLRPARRQEK LGKMLKDFLA GNSKKREEER IAKEAADAQH QLSLVQSWIN GYGQEKLADK 120
  121 KDPAKVSAS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [346-636]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FVEKYGRCQE VIGRGAFGVV RIAHKVDPQN SGSETLYAVK EFRRKPAESQ KKYTKRLTSE  60
   61 FCISSSLRHP NVIHTLDLIQ DGKGDYCEVM ELCSGGDLYT LIMAAGRLEP MEADCFFKQL 120
  121 MRGVDYLHDM GVAHRDLKPE NLLLTVSGSL KITDFGNGEC FRMAWEKEAH MTCGLCGSAP 180
  181 YIAPEEYTES EFDPRAVDVW ACGVIYMAMR TGRHLWRVAK KSEDEYYSRY LMDRKNESGY 240
  241 EPIEMLERSR CRNTLYNILH PNPTYRLTAK QIMKSEWVRS ITLCEAGNAG L

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	75.221849
Match:	2fh9A
Description:	No description for 2fh9A was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits