YRC Public Data Repository - Protein Structure Prediction

Protein:	ppk14
Organism:	Schizosaccharomyces pombe
Length:	566 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ppk14.

Description	E-value	Query Range	Subject Range
pkc-2 - status:Confirmed UniProt:P90980 protein_id:AAM51503.1	339.0	[0..7]	[566..156]
gi\|47213332 - gi\|47213332\|emb\|CAF93963.1\| unnamed protein product [Tetraodon nigroviridis]	332.0	[0..7]	[562..296]
gi\|22135803, gi\|... - gi\|30682811\|ref\|NP_849380.1\| protein kinase family protein [Arabidopsis thaliana], gi\|30682806\|ref\|N...	331.0	[0..97]	[559..24]
NRC2_NEUCR - Serine/threonine-protein kinase nrc-2 OS=Neurospora crassa GN=nrc-2 PE=3 SV=1 NRC2_NEUCR - Serine/threonine-protein kinase nrc-2 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708...	329.0	[0..2]	[566..27]
gi\|60826237 - gi\|60826237\|gb\|AAX36750.1\| protein kinase C alpha [synthetic construct]	328.0	[0..7]	[561..154]
PRKCA - protein kinase C, alpha gi\|190692009, gi... - gi\|254071371\|gb\|ACT64445.1\| protein kinase C, alpha protein [synthetic construct], gi\|190692009\|gb\|A... HGNC:9393\|MIM:17... - kinase C, alpha	327.0	[0..7]	[561..154]
KPCA_RAT - Protein kinase C alpha type OS=Rattus norvegicus GN=Prkca PE=1 SV=3 gi\|56914 - gi\|56914\|emb\|CAA30266.1\| unnamed protein product [Rattus rattus]	327.0	[0..7]	[561..154]
gi\|169620806, gi... - gi\|169620806\|ref\|XP_001803814.1\| hypothetical protein SNOG_13609 [Phaeosphaeria nodorum SN15], gi\|11...	327.0	[0..5]	[544..88]
gi\|66717, gi\|499... - gi\|74151073\|dbj\|BAE27664.1\| unnamed protein product [Mus musculus], gi\|66792589\|gb\|AAH96493.1\| Prkca... gi\|117616652 - gi\|117616652\|gb\|ABK42344.1\| protein kinase C alpha [synthetic construct]	327.0	[0..7]	[561..154]

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Predicted Domain #1

Region A:
Residues: [1-189]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNELHDGESS EEGRINVEDH LEEAKKDDTG HWKHSGTAKP SKFRAFIRLH FKDSRKFAFS  60
   61 RKKEKELTSE DSDAANQSPS GAPESQTEEE SDRKIDGTGS SAEGGDGSGT DSISVIKKSF 120
  121 FKSGRKKKDV PKSRNVSRSN GADTSVQREK LKDIFSPHGK EKELAHIKKT VATRARTYSS 180
  181 NSIKICDVE

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [190-496]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VGPSSFEKVF LLGKGDVGRV YLVREKKSGK FYAMKVLSKQ EMIKRNKSKR AFAEQHILAT  60
   61 SNHPFIVTLY HSFQSDEYLY LCMEYCMGGE FFRALQRRPG RCLSENEAKF YIAEVTAALE 120
  121 YLHLMGFIYR DLKPENILLH ESGHIMLSDF DLSKQSNSAG APTVIQARNA PSAQNAYALD 180
  181 TKSCIADFRT NSFVGTEEYI APEVIKGCGH TSAVDWWTLG ILFYEMLYAT TPFKGKNRNM 240
  241 TFSNILHKDV IFPEYADAPS ISSLCKNLIR KLLVKDENDR LGSQAGAADV KLHPFFKNVQ 300
  301 WALLRHT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	55.69897
Match:	2c30A
Description:	Crystal Structure Of The Human P21-Activated Kinase 6
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [497-566]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EPPIIPKLAP IDEKGNPNIS HLKESKSLDI THSPQNTQTV EVPLSNLSGA DHGDDPFESF  60
   61 NSVTVHHEWD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	87.522879
Match:	2jdoA
Description:	No description for 2jdoA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits