YRC Public Data Repository - Protein Structure Prediction

Protein:	ish1
Organism:	Schizosaccharomyces pombe
Length:	684 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ish1.

Description	E-value	Query Range	Subject Range
gi\|1145409 - gi\|1145409\|gb\|AAC49262.1\| orf of unknown function; Method: conceptual translation supplied by author	771.0	[0..1]	[610..1]
gi\|44982250 - gi\|44982250\|gb\|AAS51559.1\| ADL360Cp [Ashbya gossypii ATCC 10895] gi\|45187512, gi\|... - gi\|45187512\|ref\|NP_983735.1\| ADL360Cp [Ashbya gossypii ATCC 10895], gi\|44982250\|gb\|AAS51559.1\| ADL36...	489.0	[0..71]	[614..25]
gi\|28918584, gi\|... - gi\|40882205\|emb\|CAF06031.1\| related to brefeldin A resistance protein [Neurospora crassa], gi\|324063... gi\|85085366 - gi\|85085366\|ref\|XP_957492.1\| hypothetical protein NCU04415 [Neurospora crassa OR74A]	449.0	[0..3]	[561..4]
gi\|39940152, gi\|... - gi\|39940152\|ref\|XP_359613.1\| hypothetical protein MGG_05164 [Magnaporthe grisea 70-15], gb\|EAA52472....	424.0	[0..5]	[521..6]
gi\|49095232, gi\|... - gi\|67537540\|ref\|XP_662544.1\| hypothetical protein AN4940.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	417.0	[0..112]	[608..16]
gi\|46140175, gi\|... - gi\|46140175\|ref\|XP_391778.1\| hypothetical protein FG11602.1 [Gibberella zeae PH-1], gi\|42555944\|gb\|E...	397.0	[0..1]	[607..1]
MSC1_YEAST - Meiotic sister chromatid recombination protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S... MSC1 - Protein of unknown function; mutant is defective in directing meiotic recombination events to homolo...	351.0	[0..55]	[522..16]
gi\|66852208, gi\|... - gi\|70999708\|ref\|XP_754571.1\| meiotic sister chromatid recombination protein Ish1/Msc1, putative [Asp...	345.0	[0..145]	[607..66]
gi\|115396238, gi... - gi\|115396238\|ref\|XP_001213758.1\| conserved hypothetical protein [Aspergillus terreus NIH2624], gi\|11...	345.0	[0..107]	[607..11]
SPAC23C4.05c - LEA domain protein YF65_SCHPO - Uncharacterized protein C23C4.05c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC23C4...	325.0	[0..186]	[620..66]

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Predicted Domain #1

Region A:
Residues: [1-158]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRSRSVASLG VLLAIVFYIF TYGFSTYRKN DTSAVKTWLE EHSIPYGSRS SPSDFQQFIS  60
   61 ESYDSLVPNL DKWSGHNLNS WLGKKTESSY LDAISNKIRK TGRKLSGSVE DARDATQEAW 120
  121 ESQKASLFES WSDSQLRAFL ARHSPQFAAK EKKGILEK

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [159-313]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSPASLRETA AKEYDALTSK LGNTGDWIYD TWSDNELRTW LHDVGVPISS HESTRSHLLR  60
   61 KLKNYISTKA DEAQPSVEAV KGKASEKAKQ AGEFVSDKAG DAKELVNEKS SEAGQYAGQK 120
  121 MEEGGELLQE ISKRRGRFGN WWANSGLKAY FDAHG

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [314-521]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IPAYQPSPID QFYAHLRRQY YLKTNGYQAL KSKAYEEASN VADSASSIAS NVASGATEAY  60
   61 QGAASGASRF TEGAKTAAES VTSAFEHNKD TATSKAKQMK GKAASLGSTA SEKVGEAADY 120
  121 AAETASKVAS KAASKVRETI DETIIERWQD SKLKEFLFLR GVPVPQRSTK DQLLDLVRKH 180
  181 FNKGAVPNWA AYFDTLSSKE LSAWIKEY

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	2.11
Match:	1xq8A
Description:	Human micelle-bound alpha-synuclein
Matching Structure (courtesy of the PDB):

Predicted Domain #4

Region A:
Residues: [522-684]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKHYHGKLHP SKDREHLFQN ACNIYRAIAE KADKSVLQSI QSKFPKATVP GYDSWSNEDL  60
   61 KSALKEYGDS IGKVFNRKDA IERLKRHDIL FYGPVVADKA KSGVSGFLRR VASFMGFGTR 120
  121 DVAEIKLGEN IQKVKDTASK ASSAVSSAGD YVETNVKKAQ RVL

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits