YRC Public Data Repository - Protein Structure Prediction

Protein:	gly1
Organism:	Schizosaccharomyces pombe
Length:	376 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gly1.

Description	E-value	Query Range	Subject Range
ARGD_METJA - Acetylornithine aminotransferase OS=Methanocaldococcus jannaschii GN=argD PE=3 SV=1 ARGD_METJA - Acetylornithine aminotransferase OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JA...	231.0	[0..22]	[361..35]
gi\|73668410, gi\|... - gi\|73668410\|ref\|YP_304425.1\| acetylornithine aminotransferase [Methanosarcina barkeri str. Fusaro], ...	223.0	[0..7]	[355..37]
ARGD_BACHD - Acetylornithine aminotransferase OS=Bacillus halodurans GN=argD PE=3 SV=1 ARGD_BACHD - Acetylornithine aminotransferase OS=Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344...	221.0	[0..22]	[359..25]
gi\|41720336, gi\|... - gi\|91774127\|ref\|YP_566819.1\| acetylornithine aminotransferase [Methanococcoides burtonii DSM 6242], ...	221.0	[0..7]	[355..25]
ARGD_THETN - Acetylornithine aminotransferase OS=Thermoanaerobacter tengcongensis GN=argD PE=3 SV=1 ARGD_CALS4 - Acetylornithine aminotransferase OS=Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 1...	220.0	[0..7]	[360..12]
gi\|147920091, gi... - gi\|147920091\|ref\|YP_686150.1\| acetylornithine aminotransferase [uncultured methanogenic archaeon RC-...	220.0	[0..7]	[354..25]
ARGD_METAC - Acetylornithine aminotransferase OS=Methanosarcina acetivorans GN=argD PE=3 SV=1 gi\|20089018, gi\|... - gi\|20089018\|ref\|NP_615093.1\| acetylornithine aminotransferase [Methanosarcina acetivorans C2A], gi\|1...	217.0	[0..7]	[355..39]
ARGD_METMA - Acetylornithine aminotransferase OS=Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go... ARGD_METMA - Acetylornithine aminotransferase OS=Methanosarcina mazei GN=argD PE=3 SV=1	216.0	[0..7]	[355..29]
gi\|85859272, gi\|... - gi\|85859272\|ref\|YP_461474.1\| acetylornithine aminotransferase [Syntrophus aciditrophicus SB], gi\|857...	215.0	[0..7]	[358..17]
gi\|45358664, gi\|... - gi\|45358664\|ref\|NP_988221.1\| acetylornithine aminotransferase [Methanococcus maripaludis S2], gi\|450...	215.0	[0..22]	[359..38]

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Predicted Domain #1

Region A:
Residues: [1-376]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGSVTSTTT ETRLCPSNQG SAKKYRPWND FRSDTLTVPT DEMRRIMYEA SDGDCVYEED  60
   61 EDTRKLEVYV AKLTGKEAAL FVTSGTQGNQ LCIRSHLHQP PHSIICDDRA HIYNWEAGAI 120
  121 GLFTQAIVRP ISPKNNVYIT AEEIENKLIL GNDIHFSPTG LICLENTIKG AVVPLDEVAR 180
  181 ISGLAKAHKI PLHCDGARLW DAAVASNVSI KEYCSYFDSV SLCLSKGLAA PVGSIIVGPR 240
  241 DFIAKAKWFR KAYGGGLRQS GMLAAAGLYS IQHNFPLLKQ VHKYAIEVAE YAESLGIELE 300
  301 VPTQSNMVTL ANINVAILCD EAKKSGIILM GPRIVFHIQI TPDAVEILKN VLRRTVERQA 360
  361 VETHIVAKPG EFCVGY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	51.522879
Match:	2fm1A
Description:	Crystal structure of L-ALLO-threonine aldolase (tm1744) from Thermotoga maritima at 2.25 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
glycine dehydrogenase (decarboxylating) activity	2.63753310919108	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor	2.63753310919108	bayes_pls_golite062009
threonine aldolase activity	2.36742457876142	bayes_pls_golite062009
catalytic activity	2.29878871754893	bayes_pls_golite062009
L-aspartate:2-oxoglutarate aminotransferase activity	1.87460342369605	bayes_pls_golite062009
transferase activity	1.44093490824786	bayes_pls_golite062009
transferase activity, transferring nitrogenous groups	1.28316822767388	bayes_pls_golite062009
transaminase activity	1.24990480711889	bayes_pls_golite062009
O-phospho-L-serine:2-oxoglutarate aminotransferase activity	0.994935084630764	bayes_pls_golite062009
methyltransferase activity	0.681623261233707	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	0.60304280865376	bayes_pls_golite062009
binding	0.536634592992536	bayes_pls_golite062009
glycine C-acetyltransferase activity	0.367632398200112	bayes_pls_golite062009
glycine hydroxymethyltransferase activity	0.271623203801431	bayes_pls_golite062009
pyridoxal phosphate binding	0.16957228630576	bayes_pls_golite062009
vitamin B6 binding	0.16957228630576	bayes_pls_golite062009
L-allo-threonine aldolase activity	0.140152839681041	bayes_pls_golite062009
carbon-carbon lyase activity	0.11598778799668	bayes_pls_golite062009
4-aminobutyrate transaminase activity	0.0779403509221881	bayes_pls_golite062009
nucleic acid binding	0.013097682076602	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: