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View Structure Prediction Details

Protein: ght2
Organism: Schizosaccharomyces pombe
Length: 531 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ght2.

Description E-value Query
Range
Subject
Range
gi|11277423, gi|... - gi|2407189|gb|AAB70519.1| hexose transporter [Schizosaccharomyces pombe], pir||T43533 hexose transpo...
280.0 [0..13] [531..1]
gi|115402325, gi... - gi|115402325|ref|XP_001217239.1| hypothetical protein ATEG_08653 [Aspergillus terreus NIH2624], gi|1...
268.0 [0..2] [521..41]
gi|49527412 - gi|49527412|emb|CAG61052.1| unnamed protein product [Candida glabrata]
gi|50291337, gi|... - gi|50291337|ref|XP_448101.1| unnamed protein product [Candida glabrata], gi|49527412|emb|CAG61052.1|...
264.0 [0..2] [519..111]
GHT1_SCHPO - High-affinity glucose transporter ght1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=ght...
ght1 - hexose transporter Ght1
264.0 [0..11] [529..7]
orf19.2020, orf1... - HGT6 CGDID:CAL0004351 Assembly 19, Contig19-10139 (66413, 64761) CDS, reverse complemented, translat...
gi|68472555, gi|... - gi|68472808|ref|XP_719469.1| potential hexose transporter [Candida albicans SC5314], gi|68472555|ref...
261.0 [0..12] [508..52]
KHT2_KLULC - Hexose transporter 2 OS=Kluyveromyces lactis GN=KHT2 PE=3 SV=1
257.0 [0..12] [502..64]
gi|171554 - gi|171554|gb|AAA34624.1| galactose permease
254.0 [0..12] [502..73]

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Predicted Domain #1
Region A:
Residues: [1-531]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGFKRGKNFT LVMLIFVSMA GWMFGADTGS IGGVTSMRDF RERYADRYDP ITDQYSLSSA  60
   61 RQGLLTGMVN VGSLFGCIIS SPIADRFGKR LSIIGFCAVY IIGIIVQVTA VPSWVQIMVA 120
  121 KIWTGIGIGA LSVLAPGYQS ETAPPSIRGT VVVTYQLFVT GGIFIAACIN MGTHKLHKTA 180
  181 QWRVSIGINL LWGIITMIGI LFLPESPRYL IQVGKDEEAV RVLSESAELF PDSEEVQNEY 240
  241 HRLKSSIDEE FAGGPCSWAS IFGKDIRYRT FLGMFVMSLQ QLTGNNYFFY YGFSVMQGAG 300
  301 INSPYLSAMI LDAVNFGCTF GGMYVLERFG RRNPLIIGGI WQSICFFIYS AVGSRALYHK 360
  361 NGTSNTRAGA VMIVMACLFI FGFAQTWAPA AYVIVGESYP VRYRSKCAAV ATASNWLWNF 420
  421 LISFFTPFIQ ASIGFKYGYV FASCNLTGAI VIFLFAKETK GLTLEEINEL YMSVIKPWES 480
  481 GNFKLNYSEQ KKVEKEKSRK GGARGESVEY VERASNTDSS PQYSSHEEDY A

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.30103
Match: 1pw4A
Description: Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
glycerol transmembrane transporter activity 7.11654923455995 bayes_pls_golite062009
alcohol transmembrane transporter activity 6.7545566917184 bayes_pls_golite062009
polyol transmembrane transporter activity 6.7545566917184 bayes_pls_golite062009
glycerol-3-phosphate transmembrane transporter activity 5.74077413704789 bayes_pls_golite062009
transporter activity 4.09176719149278 bayes_pls_golite062009
substrate-specific transporter activity 3.59744164024479 bayes_pls_golite062009
transmembrane transporter activity 3.5865018981083 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 3.54194478414824 bayes_pls_golite062009
hexose phosphate transmembrane transporter activity 3.3746965264994 bayes_pls_golite062009
glucose-6-phosphate transmembrane transporter activity 3.3746965264994 bayes_pls_golite062009
sugar:hydrogen symporter activity 2.99050613058546 bayes_pls_golite062009
cation:sugar symporter activity 2.99050613058546 bayes_pls_golite062009
monosaccharide transmembrane transporter activity 2.63293544825311 bayes_pls_golite062009
carbohydrate transmembrane transporter activity 2.62141276633776 bayes_pls_golite062009
sugar transmembrane transporter activity 2.47557586092261 bayes_pls_golite062009
ion transmembrane transporter activity 2.21266150105753 bayes_pls_golite062009
solute:hydrogen symporter activity 2.10485633822652 bayes_pls_golite062009
binding 1.89539096965643 bayes_pls_golite062009
cation transmembrane transporter activity 1.79369588808394 bayes_pls_golite062009
active transmembrane transporter activity 1.59419818573076 bayes_pls_golite062009
secondary active transmembrane transporter activity 1.22264637452409 bayes_pls_golite062009
symporter activity 0.74591237387473 bayes_pls_golite062009
solute:cation symporter activity 0.74591237387473 bayes_pls_golite062009
sugar binding 0.285073104957756 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle