YRC Public Data Repository - Protein Structure Prediction

Protein:	erg25
Organism:	Schizosaccharomyces pombe
Length:	300 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for erg25.

Description	E-value	Query Range	Subject Range
gi\|42554849, gi\|... - gi\|46136629\|ref\|XP_390006.1\| hypothetical protein FG09830.1 [Gibberella zeae PH-1], gi\|42554849\|gb\|E...	250.0	[0..1]	[299..4]
gi\|45269545 - gi\|45269545\|gb\|AAS56153.1\| YGR060W [Saccharomyces cerevisiae]	249.0	[0..2]	[300..7]
gi\|107785178, gi... - gi\|107785180\|gb\|ABF84061.1\| C-4 sterol methyl oxidase [Chaetomium globosum], gi\|107785178\|gb\|ABF8406...	248.0	[0..1]	[299..6]
gi\|83775259 - gi\|83775259\|dbj\|BAE65381.1\| unnamed protein product [Aspergillus oryzae] gi\|169784105 - gi\|169784105\|ref\|XP_001826514.1\| hypothetical protein [Aspergillus oryzae RIB40]	246.0	[0..1]	[299..5]
gi\|85106720 - gi\|85106720\|ref\|XP_962240.1\| C-4 methylsterol oxidase, variant [Neurospora crassa OR74A] gi\|28923840, gi\|... - gi\|32411553\|ref\|XP_326257.1\| hypothetical protein [Neurospora crassa], gi\|28923840\|gb\|EAA33004.1\| C-...	246.0	[0..1]	[287..6]
gi\|70982279, gi\|... - gi\|70982279\|ref\|XP_746668.1\| C-4 methyl sterol oxidase Erg25 [Aspergillus fumigatus Af293], gi\|66844...	246.0	[0..1]	[295..1]
gi\|68466442, gi\|... - gi\|68466442\|ref\|XP_722703.1\| potential C-4 sterol methyl oxidase [Candida albicans SC5314], gi\|46444... orf19.4631 - ERG251 CGDID:CAL0003665 Assembly 19, Contig19-10212 (132343, 133308) CDS, translated using codon tab...	239.0	[0..2]	[300..10]
gi\|44985165, gi\|... - gi\|45199090\|ref\|NP_986119.1\| AFR572Wp [Ashbya gossypii ATCC 10895], gi\|44985165\|gb\|AAS53943.1\| AFR57... gi\|44985165 - gi\|44985165\|gb\|AAS53943.1\| AFR572Wp [Ashbya gossypii ATCC 10895]	238.0	[0..2]	[300..7]

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Predicted Domain #1

Region A:
Residues: [1-124]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNTTSEVIVG TGFQAIRQQL AQMHPELNFV EQLWLAYYKW FDNDVVATGL MSFLLHELIY  60
   61 FGRCIPWMII DAMPYFRRWK IQPKKVPTLA EQWECTRLVL LSHFTVELPQ IWLFDPMCAT 120
  121 FGLS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [125-300]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSVPFPPVTK MIWQITLFFF LEDTWHYWAH RLFHYGIFYR FIHKVHHRYS APFGLSAEYA  60
   61 HPLEIILLGA GTVFVPLMWC YFTHDLHLVT MYIWITLRLF QAVDSHAGYD FPWSLNKFLP 120
  121 IWAGADHHDY HHMAFKDNFS SSFRWWDAVL KTDQNYHQFK ARRLAAKYEA ESKKAK

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	0.986
Match:	2f5kA
Description:	No description for 2f5kA was found.

Predicted functions:

Term	Confidence	Notes
binding	2.10787756282836	bayes_pls_golite062009
transcription regulator activity	1.56029029012385	bayes_pls_golite062009
chromatin binding	1.51511928418505	bayes_pls_golite062009
transcription repressor activity	0.991756552156335	bayes_pls_golite062009
protein binding	0.759327550978008	bayes_pls_golite062009
nucleic acid binding	0.57519986764207	bayes_pls_golite062009
DNA binding	0.293109488455755	bayes_pls_golite062009
catalytic activity	0.168308115787289	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: