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View Structure Prediction Details

Protein: cit1
Organism: Schizosaccharomyces pombe
Length: 473 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cit1.

Description E-value Query
Range
Subject
Range
CISY_XENLA - Citrate synthase, mitochondrial OS=Xenopus laevis GN=cs PE=2 SV=1
552.0 [0..8] [473..1]
gi|14423562, gi|... - gi|30387583|gb|AAP31957.1| At2g44350 [Arabidopsis thaliana], gi|20197191|gb|AAC16084.2| citrate synt...
552.0 [0..6] [471..3]
CISY_XENTR - Citrate synthase, mitochondrial OS=Xenopus tropicalis GN=cs PE=2 SV=1
549.0 [0..8] [473..1]
CISY_DAUCA - Citrate synthase, mitochondrial OS=Daucus carota GN=CS PE=2 SV=1
548.0 [0..6] [471..3]
CISY_MOUSE - Citrate synthase, mitochondrial OS=Mus musculus GN=Cs PE=1 SV=1
545.0 [0..16] [473..3]
CISY_MACFA - Citrate synthase, mitochondrial OS=Macaca fascicularis GN=CS PE=2 SV=1
ENSMMUT000000035... - null, null
545.0 [0..30] [473..21]
CISY_DANRE - Citrate synthase, mitochondrial OS=Danio rerio GN=cs PE=2 SV=1
545.0 [0..12] [473..5]
gi|114644121 - gi|114644121|ref|XP_001153202.1| PREDICTED: citrate synthase [Pan troglodytes]
544.0 [0..30] [473..21]

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Predicted Domain #1
Region A:
Residues: [1-473]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTNTRLASTR RLASSLLSQA SLRSRQLNPL FTSSYSTRSS SLKDRLAELI PEKQAEIKKF  60
   61 RAEHGQDVIG EVTINQMYGG ARGVRSLIWE GSVLDPNEGI RFRGYTIPEC QKLLPSSPNG 120
  121 KQPLPESLFW LLVTGEIPTL SQVQALSADW AARSQLPKFV EELIDRCPPT LHPMAQFSLA 180
  181 VTALEHDSAF AKAYERGMNK HDYWKYEYED CMDLIAKTVP IAGRIYRNLY RDGVVAPIQM 240
  241 DKDHSYNFAN VLGFANNEEF VELMRLYLTI HADHEGGNVS AHTGHLVGSA LSSPFLSMAA 300
  301 SLNGLAGPLH GLANQEVLNF LITMKKEIGD DLSEETIKSY LWKLLNSGRV VPGYGHAVLR 360
  361 KTDPRYTAQR EFALEHLPKD PMFQLVSRLY EIVPGVLTEH GKTKNPYPNV DSHSGVLLQY 420
  421 YGLKEQSFYT VLFGVSRTLG VASQLIWDRA LGLPIERPKS FSTEALKKMV ETK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 154.0
Match: 1ctsA
Description: CRYSTALLOGRAPHIC REFINEMENT AND ATOMIC MODELS OF TWO DIFFERENT FORMS OF CITRATE SYNTHASE AT 2.7 AND 1.7 ANGSTROMS RESOLUTION
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
citrate (Si)-synthase activity 7.90380661459876 bayes_pls_golite062009
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer 7.35970609422108 bayes_pls_golite062009
transferase activity, transferring acyl groups 4.98392594633005 bayes_pls_golite062009
catalytic activity 2.51855037019879 bayes_pls_golite062009
transferase activity 2.22659761972612 bayes_pls_golite062009
binding 1.15467737113069 bayes_pls_golite062009
protein binding 0.210158634792359 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle