YRC Public Data Repository - Protein Structure Prediction

Protein:	fba1
Organism:	Schizosaccharomyces pombe
Length:	358 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for fba1.

Description	E-value	Query Range	Subject Range
gi\|49091102, gi\|... - gi\|67524835\|ref\|XP_660479.1\| hypothetical protein AN2875.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	468.0	[0..1]	[358..1]
gi\|70999466, gi\|... - gi\|70999466\|ref\|XP_754452.1\| fructose-bisphosphate aldolase, class II [Aspergillus fumigatus Af293],... gi\|159127469 - gi\|159127469\|gb\|EDP52584.1\| fructose-bisphosphate aldolase, class II [Aspergillus fumigatus A1163]	468.0	[0..1]	[358..1]
gi\|71004310, gi\|... - gi\|71004310\|ref\|XP_756821.1\| hypothetical protein UM00674.1 [Ustilago maydis 521], ref\|XP_398289.1\| ...	467.0	[0..1]	[358..1]
gi\|46451700, gi\|... - gi\|74664643\|sp\|Q96UH7.2\|ALF1_PARBR RecName: Full=Fructose-bisphosphate aldolase 1; Short=FBP aldolas...	465.0	[0..1]	[358..1]
gi\|115396484, gi... - gi\|115396484\|ref\|XP_001213881.1\| fructose-bisphosphate aldolase [Aspergillus terreus NIH2624], gi\|11...	463.0	[0..1]	[358..1]
gi\|42544493, gi\|... - gi\|46111777\|ref\|XP_382946.1\| hypothetical protein FG02770.1 [Gibberella zeae PH-1], gi\|42544493\|gb\|E...	462.0	[0..1]	[358..1]
gi\|111606549 - gi\|111606549\|gb\|ABH10639.1\| fructose biphosphate aldolase [Coccidioides posadasii] gi\|240108278 - gi\|240108278\|gb\|EER26452.1\| Fructose 1,6-bisphosphate aldolase, putative [Coccidioides posadasii C73...	461.0	[0..1]	[358..1]
ALF_EDWIC - Fructose-bisphosphate aldolase OS=Edwardsiella ictaluri GN=fba PE=3 SV=1 gi\|2708661\|gb\|AA... - fructose 1,6-bisphosphate aldolase [Edwardsiella ictaluri]	461.0	[0..3]	[358..4]
gi\|90302999, gi\|... - gi\|90302999\|gb\|EAS32630.1\| hypothetical protein CIMG_03654 [Coccidioides immitis RS], gi\|119187213\|r...	461.0	[0..1]	[358..1]
gi\|111063382, gi... - gi\|169610259\|ref\|XP_001798548.1\| hypothetical protein SNOG_08226 [Phaeosphaeria nodorum SN15], gi\|11...	461.0	[0..1]	[358..1]

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Predicted Domain #1

Region A:
Residues: [1-358]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGILDIVPTG VITGDNVLKL FTYAREHGFA IPAINVTSSS TAIAALEAAR EARSPIILQT  60
   61 SNGGAHFFAG KESSNEGQKA SIAGSIAAAH YIRSIAPFFG VPVVMHSDHC AKKLLPWMDG 120
  121 MFEADEAYFK IHGEPLFSSH MLDLSEEPKK ENIAQVKEYC KRAVPMKIWI EMEIGITGGE 180
  181 EDGVDNSHVS HTELYTQPED IWDVYRELSS VTPYFSIAAA FGNVHGVYKP GNVKLQPALL 240
  241 GQHQAYVKEQ LKTTNDKPVF FVFHGGSGSS VNEFRTGIKC GVVKVNIDTD TQFAYVEGVR 300
  301 DYVLKYKDYL MTPVGNPEGA DKPNKKKFDP RVWIHEGEKT MTKRVLTALE DFYTVNTL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	128.0
Match:	1b57A
Description:	Fructose-bisphosphate aldolase (FBP aldolase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.67031204377352	bayes_pls_golite062009
fructose-bisphosphate aldolase activity	2.5119145652386	bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups	2.0240718059985	bayes_pls_golite062009
transaldolase activity	1.66628808988861	bayes_pls_golite062009
binding	1.1388634428163	bayes_pls_golite062009
lyase activity	0.740424046054758	bayes_pls_golite062009
transferase activity	0.464721888799972	bayes_pls_golite062009
aldehyde-lyase activity	0.351872954170322	bayes_pls_golite062009
signal transducer activity	0.348681535897548	bayes_pls_golite062009
molecular transducer activity	0.348681535897548	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	0.25728790872659	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: