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View Structure Prediction Details

Protein: slgA-PD
Organism: Drosophila melanogaster
Length: 681 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for slgA-PD.

Description E-value Query
Range
Subject
Range
slgA-PE, FBpp0300184 - The gene sluggish A is referred to in FlyBase by the symbol Dmel\slgA (CG1417, FBgn0003423). It is a...
764.0 [0..1] [681..1]

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Predicted Domain #1
Region A:
Residues: [1-85]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALLRSLSAQ RTAISLVYGR NSSKSSNSVA VAACRSFHQR GSGSTSIAGE GAASESTRGV  60
   61 NGARFLHSGD RPLQASTLVQ PEVVS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [86-681]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SETVKRSMKQ ESSQEKNPSP AGSPQRDPLD VSFNDPIAAF KSKTTGELIR AYLVYMICSS  60
   61 EKLVEHNMTL MKLARNLLGQ KLFVLLMKSS FYGHFVAGEN RHTIVPALER LRSFGVKPIL 120
  121 DYSVEEDITQ EEAEKREVES SVSSAGDKKE EGSMPQYHVD KSFADRRYKV SSARTYFYLN 180
  181 EATCERNMEI FIKCLEAVSD DDRKAPRAVA TGATFGTGIT AIKLTALGRP QLLLQLSEVI 240
  241 MRTRKYMEDM VGGQGNVLTH HKTIKDLEKY YATLGDNKDV KEFLNNVTSD KEGILHLFPW 300
  301 SGIVDEDSQL SDTFRVPDPQ TGQMRRLISQ IPPKEEEMFR NMIRRLNTIV KAAADLDVRI 360
  361 MVDAEQTYFQ PAISRITLEM MRKYNKDKAI VFNTYQCYLR ETFREVNTDL EQAKRQNFYF 420
  421 GAKLVRGAYM DQERDRAKSL GYPDPVNPTF EATTDMYHRT LSECLRRIKL MKDCDDDARK 480
  481 IGIMVASHNE DTVRFAIQQM KEIGISPEDK VICFGQLLGM CDYITFPLGQ AGYSAYKYIP 540
  541 YGPVEEVLPY LSRRAQENKG VLKKIKKEKR LLLSEIRRRL MRGQLFYKPK GNYVPI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 123.0
Match: 1k87A
Description: N-terminal domain of bifunctional PutA protein; Proline dehydrohenase domain of bifunctional PutA protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxidoreductase activity, acting on the CH-NH group of donors 6.88732579226533 bayes_pls_golite062009
1-pyrroline-5-carboxylate dehydrogenase activity 6.68550231605226 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 5.85251457886657 bayes_pls_golite062009
oxidoreductase activity 3.26500423104107 bayes_pls_golite062009
catalytic activity 2.15527229494088 bayes_pls_golite062009
methylenetetrahydrofolate reductase (NADPH) activity 1.53575450131902 bayes_pls_golite062009
protein binding 1.38007868564575 bayes_pls_golite062009
binding 1.32681091506724 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle