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View Structure Prediction Details

Protein: RhoGAP18B-PB, Rh...
Organism: Drosophila melanogaster
Length: 468 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RhoGAP18B-PB, Rh....

Description E-value Query
Range
Subject
Range
gi|76668333 - gi|76668333|ref|XP_869529.1| PREDICTED: similar to Rho GTPase activating protein 12 isoform 2 [Bos t...
302.0 [0..4] [460..368]

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Predicted Domain #1
Region A:
Residues: [1-167]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGDTENKRG YRTIFRSISQ VFYANAKNSS NTNSSSSNNN NNIINYNNNT IENNNEGIGQ  60
   61 LTVTLTSITP PTATWTSTSP TISTCTTASA SAGSSTASLS PLASRSARSA ENISCSECGN 120
  121 PDPYHGQDME LAKGQALTPE VPAVPVPAAS ADQNQKLRAS SMLDLTS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.522879
Match: 2p0dA
Description: No description for 2p0dA was found.

Predicted Domain #2
Region A:
Residues: [168-468]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NHRHQNGLRI VPVTDILRAQ QIQEDNEVQQ TQQSTILQRY KSVSIGNLLD LPGEDDKKSI  60
   61 KNRMRMKFAV NSNVFRINRS PKSEKKSRSR RGQVNSLYLD EQKYPLFAAP LSALELNMTD 120
  121 HPNVPRFVVD VCAYIEQPEC IEQDGLYRAS GNKVLVDELR KKLTHVYDPR WLKTDDIHTL 180
  181 TSLHKQFFRE LTSPLITQEA YERLGRSLND DAAIERMSLA FDDMPEPNRS TLRFLIRHLT 240
  241 RVAAASASNR MPSTNLAIVW GPCLLSANQI QLDIGRMNML AKVLIENYDR IFHPDNERLV 300
  301 C

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.0
Match: 1xa6A
Description: Crystal Structure of the Human Beta2-Chimaerin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
enzyme activator activity 0.53004209819211 bayes_pls_golite062009
GTPase activator activity 0.528693496432149 bayes_pls_golite062009
binding 0.0980674097362609 bayes_pls_golite062009
Ras GTPase activator activity 0.0454578418356197 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle