YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: Pvf1-PA
Organism: Drosophila melanogaster
Length: 325 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Pvf1-PA.

Description E-value Query
Range
Subject
Range
Pvf1-PB - The gene PDGF- and VEGF-related factor 1 is referred to in FlyBase by the symbol Dmel\Pvf1 (CG7103, ...
263.0 [0..29] [325..18]

Back

Predicted Domain #1
Region A:
Residues: [1-71]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAMSRIRILK PMQHPLLILP VLLLVLIVSE AAAGSLVSPN NRQPSQRFFY AAATSSSSTQ  60
   61 TKVRLLRQAD D

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [72-230]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSAAPGALEG SCCQGAAAEA GTPLTLPLSV SAELTNVTAD YDVSGEMPSS KENFKRSIMK  60
   61 STVRNATPAS CSPQPTIVEL KPPAEDEANY YYMPACTRIS RCNGCCGSTL ISCQPTEVEQ 120
  121 VQLRVRKVDR AATSGRRPFT IITVEQHTQC RCDCRTKAE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.69897
Match: 1fzvA
Description: Placenta growth factor-1, PLGF-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
vascular endothelial growth factor receptor binding 5.53296544131638 bayes_pls_golite062009
receptor binding 4.98600168355158 bayes_pls_golite062009
vascular endothelial growth factor receptor 2 binding 4.84894440498579 bayes_pls_golite062009
growth factor activity 4.40342630446728 bayes_pls_golite062009
vascular endothelial growth factor receptor 1 binding 3.72494469310902 bayes_pls_golite062009
receptor serine/threonine kinase binding 3.60727548920187 bayes_pls_golite062009
transmembrane receptor protein serine/threonine kinase binding 3.46872954776606 bayes_pls_golite062009
transforming growth factor beta receptor binding 3.46872954776606 bayes_pls_golite062009
cytokine activity 2.94824371215551 bayes_pls_golite062009
binding 2.64101807129423 bayes_pls_golite062009
vascular endothelial growth factor receptor 3 binding 2.49662692173028 bayes_pls_golite062009
growth factor binding 2.41942870726502 bayes_pls_golite062009
protein binding 2.36794464190805 bayes_pls_golite062009
cell surface binding 2.18650685174299 bayes_pls_golite062009
platelet-derived growth factor receptor binding 1.78479767888975 bayes_pls_golite062009
type II transforming growth factor beta receptor binding 1.68851021785811 bayes_pls_golite062009
pattern binding 1.42097884493181 bayes_pls_golite062009
heparin binding 1.29079171602988 bayes_pls_golite062009
glycosaminoglycan binding 1.20536536478688 bayes_pls_golite062009
platelet-derived growth factor binding 1.16893591942376 bayes_pls_golite062009
hormone activity 0.94314407550729 bayes_pls_golite062009
fibronectin binding 0.81652439411811 bayes_pls_golite062009
protein dimerization activity 0.697058311884552 bayes_pls_golite062009
polysaccharide binding 0.539968806788969 bayes_pls_golite062009
protein homodimerization activity 0.415660572795793 bayes_pls_golite062009
carbohydrate binding 0.40503978964895 bayes_pls_golite062009
neurotrophin receptor binding 0.35766568682861 bayes_pls_golite062009
identical protein binding 0.273591586673912 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [231-325]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DCNVYQSYRK DLCRCECHNT DARDKCLEQA ENKYWVDDNC TCVCRYNQSC TTGTVFDETQ  60
   61 CKCTDPAAPI DVLDRKRFIV QAVQVDPDNT TLYSV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.69897
Match: 1jv2B
Description: Hybrid domain of integrin beta; Integrin beta A domain; Integrin beta tail domain; Integrin beta EGF-like domains
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle