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View Structure Prediction Details

Protein: FBpp0074230, par...
Organism: Drosophila melanogaster
Length: 351 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0074230, par....

Description E-value Query
Range
Subject
Range
gi|54643619, gi|... - gi|54643619|gb|EAL32362.1| GA19201 [Drosophila pseudoobscura pseudoobscura], gi|125983080|ref|XP_001...
gi|54643619|gb|E... - GA19201-PA [Drosophila pseudoobscura], GA19201 [Drosophila pseudoobscura pseudoobscura]
244.0 [0..1] [351..1]

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Predicted Domain #1
Region A:
Residues: [1-131]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKNKINTTS ATAASDTNLI EVKSKFDAEF RRWSFKRNEA EQSFDKFASL IEQLHKLTNI  60
   61 QFLILYIDPR DNDLLPINND DNFGRALKTA RPLLRVIVQR KDDLNEYSGF GTMKPRNLIG 120
  121 SILMGHTPVK T

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.69897
Match: 1wmhB
Description: Crystal structure of a PB1 domain complex of Protein kinase c iota and Par6 alpha
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.60223908046747 bayes_pls_golite062009
protein binding 1.04550817342273 bayes_pls_golite062009
signal transducer activity 0.397569963508051 bayes_pls_golite062009
molecular transducer activity 0.397569963508051 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [132-267]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KAPSISIPHD FRQVSAIIDV DIVPETHRRV RLLKHGSDKP LGFYIRDGTS VRVTASGLEK  60
   61 QPGIFISRLV PGGLAESTGL LAVNDEVIEV NGIEVAGKTL DQVTDMMVAN SSNLIITVKP 120
  121 ANQRTLTSTH RGSFSR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.522879
Match: 1ry4A
Description: NMR Structure of the CRIB-PDZ module of Par-6
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.6196222853442 bayes_pls_golite062009
cytoskeletal protein binding 2.48224018205024 bayes_pls_golite062009
protein binding 2.35875654816667 bayes_pls_golite062009
actin binding 1.28302718651984 bayes_pls_golite062009
transporter activity 1.18978519116375 bayes_pls_golite062009
transmembrane transporter activity 1.07211582292329 bayes_pls_golite062009
substrate-specific transporter activity 0.755223974149211 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.549085929250683 bayes_pls_golite062009
PDZ domain binding 0.53069705861477 bayes_pls_golite062009
guanylate cyclase inhibitor activity 0.434298747650806 bayes_pls_golite062009
cyclase inhibitor activity 0.434298747650806 bayes_pls_golite062009
protein domain specific binding 0.30840185305841 bayes_pls_golite062009
ErbB-2 class receptor binding 0.261656236234201 bayes_pls_golite062009
active transmembrane transporter activity 0.252733105474942 bayes_pls_golite062009
molecular transducer activity 0.211809989510755 bayes_pls_golite062009
signal transducer activity 0.211809989510755 bayes_pls_golite062009
receptor binding 0.00333430733556384 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [268-351]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSQLSSGSHH TNNTNTSDEI EHDDQDDIVD LTGVTLDESP TSTSAGNHNH QPPLSSSPSS  60
   61 HHQQAASNAS TIMASDVKDG VLHL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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