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View Structure Prediction Details

Protein: CG4351-PA
Organism: Drosophila melanogaster
Length: 757 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG4351-PA.

Description E-value Query
Range
Subject
Range
gi|54643995, gi|... - gi|54643995|gb|EAL32738.1| GA18127-PA [Drosophila pseudoobscura], gi|125983828|ref|XP_001355679.1| G...
614.0 [0..9] [757..1]

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Predicted Domain #1
Region A:
Residues: [1-291]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGAKNRQVK NVIRPRYYSS ELGIREKLFI GVMTSQEHIN TFATAFNRTT AHLVNKIKFF  60
   61 IYADSVKTNY KLKNIVGFTD TRESRRPFHV VKYIADNYLD EYDYFLLVPD TVYVDARKLV 120
  121 KLLYHMSITF DLYMGGARIG LDPSGGGASA DGQSNEPPAN EEEAPGASDR NYCSLEAGIL 180
  181 LSSSVIRKMR NNLERCVRIG STSDHSVNIG RCVKYASRVA GCQESFQGMR QFSYALDAPG 240
  241 RRHREFSELA KEEAFRNAST VYPVQTPEDF YRLHAYYSKH HLEKVQERGY A

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.221849
Match: 2j0aA
Description: No description for 2j0aA was found.

Predicted Domain #2
Region A:
Residues: [292-394]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LEQKSYRIAN GSISNKILEI RWPLGVPPPS APETRHDILT WQLLNGTHNF LPNGNAEHAV  60
   61 ATLSRIEAQD FAKVLEIALQ YAALKHPRLS YHSLHSAYRK FDA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [395-757]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TRGMDYQLHL NLQEGSGRSR RLVIKSFEVV KPLGRVEVVP SPYVTESTRI AMLVPAFEHQ  60
   61 VPDALLFVEQ YERICMQNQD NTFLLLIFMY RLESPSKGDE DPFKALKTLA LDLSSKYKTD 120
  121 GSRIAWVSIR LPEQLSEPVD PQSWLLHASM YGPRQLLSLV VADLALPKLG LESLVLLATP 180
  181 GMVFKADFLN RVRMNTIQGF QVYAPIGFQM YPCRWAHFCR ECDTCDVSQS SGYFDRHNHD 240
  241 VIAFYSRDYV QARKLLHPQG LPIIRSDLDI DQLLLQPGEE TRPPGVESIL DMFVAAQHSV 300
  301 HILRGVEPNL RFGQDVRNHL ARGGTLPQSV PERCGREQCI HLASRKQIGD AIIRYEDKSI 360
  361 LHK

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.34
Match: 1fr8A
Description: beta 1,4 galactosyltransferase (b4GalT1)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
glucuronosyltransferase activity 2.27380372964895 bayes_pls_golite062009
catalytic activity 1.73979371332125 bayes_pls_golite062009
transferase activity, transferring hexosyl groups 1.64579615957842 bayes_pls_golite062009
UDP-glycosyltransferase activity 1.18238034321908 bayes_pls_golite062009
transferase activity 1.18156663897445 bayes_pls_golite062009
heparan sulfate N-acetylglucosaminyltransferase activity 0.688664286884604 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.564357748665652 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 0.539883035270389 bayes_pls_golite062009
nucleotidyltransferase activity 0.218795796569067 bayes_pls_golite062009
acetylgalactosaminyltransferase activity 0.130891646999536 bayes_pls_golite062009
glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity 0.086807349747577 bayes_pls_golite062009
N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity 0.0571343161643402 bayes_pls_golite062009
UDP-N-acetylglucosamine diphosphorylase activity 0.0309517682490415 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle