YRC Public Data Repository - Protein Structure Prediction

Protein:	CG2200-PA, FBpp0...
Organism:	Drosophila melanogaster
Length:	240 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG2200-PA, FBpp0....

Description	E-value	Query Range	Subject Range
PEPE_HAEI8 - Peptidase E OS=Haemophilus influenzae (strain 86-028NP) GN=pepE PE=3 SV=1	223.0	[0..4]	[236..1]
gi\|53733345 - gi\|53733345\|ref\|ZP_00156410.2\| COG3340: Peptidase E [Haemophilus influenzae R2866] gi\|145638495, gi... - gi\|145638495\|ref\|ZP_01794104.1\| peptidase E [Haemophilus influenzae PittII], gi\|145272090\|gb\|EDK1199...	222.0	[0..4]	[236..1]
gi\|46143863 - gi\|46143863\|ref\|ZP_00133840.2\| COG3340: Peptidase E [Actinobacillus pleuropneumoniae serovar 1 str. ... PEPE_ACTP2 - Peptidase E OS=Actinobacillus pleuropneumoniae serotype 5b (strain L20) GN=pepE PE=3 SV=1	220.0	[0..4]	[236..1]
gi\|46128830 - gi\|46128830\|ref\|ZP_00154337.2\| COG3340: Peptidase E [Haemophilus influenzae R2846]	216.0	[0..7]	[236..1]
PEPE_XENLA - Alpha-aspartyl dipeptidase OS=Xenopus laevis GN=aad-a PE=1 SV=1	216.0	[0..1]	[238..2]
gi\|46156273, gi\|... - gi\|46156273\|ref\|ZP_00133144.2\| COG3340: Peptidase E [Haemophilus somnus 2336], gi\|170719006\|ref\|YP_0... gi\|53692699, gi\|... - gi\|53692699\|ref\|ZP_00347395.1\| COG3340: Peptidase E [Haemophilus somnus 129PT], gi\|113461388\|ref\|YP_...	216.0	[0..4]	[236..1]
gi\|12720709, gi\|... - gi\|15602319\|ref\|NP_245391.1\| peptidase E [Pasteurella multocida subsp. multocida str. Pm70], gi\|1272...	213.0	[0..1]	[236..1]
PEPE_PASMU - Peptidase E OS=Pasteurella multocida GN=pepE PE=3 SV=2 PEPE_PASMU - Peptidase E OS=Pasteurella multocida (strain Pm70) GN=pepE PE=3 SV=2	210.0	[0..4]	[236..1]
gi\|62858291, gi\|... - gi\|62858291\|ref\|NP_001016448.1\| dipeptidase E [Xenopus (Silurana) tropicalis], gi\|213625502\|gb\|AAI70...	209.0	[0..1]	[238..2]
PEPE_NOSS1 - Peptidase E OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=pepE PE=3 SV=1	208.0	[0..3]	[240..1]

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Predicted Domain #1

Region A:
Residues: [1-240]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASARNLLLL SSSRLHGHGY LEHARGQLED LFKSANVKTV LFVPYALRDH DKYTATVRDA  60
   61 LQPWGFNVEG LHTKPDREQA LREAQAIFVG GGNTFVLLRS LYEMKLLDPI RELVLQRGLP 120
  121 YVGSSAGTNV ATRSIHTTND MPVAYPPSFE ALALVPFNIN PHYLDPEAGS RHKGETRDER 180
  181 LEEFVAYHGL PVLGLREGTS VRVQGEKAIL LGDRNAKLFK ADGGTEELAP LADLTFLLQK 240
  241

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	45.0
Match:	1fy2A
Description:	Aspartyl dipeptidase PepE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.30391542469987	bayes_pls_golite062009
ligase activity	1.03859358394018	bayes_pls_golite062009
peptidase activity	0.931946117157141	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	0.422021910110542	bayes_pls_golite062009
hydrolase activity	0.121916378202276	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: