YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: tomosyn-PA, tomo...
Organism: Drosophila melanogaster
Length: 1173 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tomosyn-PA, tomo....

Description E-value Query
Range
Subject
Range
gi|157114677, gi... - gi|157114677|ref|XP_001652368.1| tomosyn [Aedes aegypti], gi|108877187|gb|EAT41412.1| tomosyn [Aedes...
786.0 [0..42] [1173..1]

Back

Predicted Domain #1
Region A:
Residues: [1-76]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKFTFKGVL DGFRQSVQPQ ATRQEQEIQE QLKADHFTLK KTFRHGFPYS PTSFAFDPVQ  60
   61 KLLAIGDKSG YIRILG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 72.69897
Match: 1vyhC
Description: PAF-AH Holoenzyme: Lis1/Alfa2
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [77-415]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RPGVDAHAKH EGESECAVLF AQFLVNEGAL VTVTADDTIH LWSIRQKTPR IVQSLKFQRE  60
   61 RVTCIHLPVG SKWLYVGTEK GNIHVVHIDT FALSGYIINW NKAIEVVRTS HPGAVIALCD 120
  121 NPLDANKLLI AFECGLLVLW DLKAKCAELR WQAAEAVKSL AWHYEGKYFV SSHTDGSICS 180
  181 WPTKPQAKPQ SQVCPHAKIN KDGNAEKCKP IYKVDLKSSA TGETFTIFSG GMPSEKGSKS 240
  241 NCITVMVGKA TTVLEMEHAV CDFITLCENP WPCETQEPYA IAVLLQYDLV LIDLLTPGFP 300
  301 CFESPYPMDL HESPVTCCTY LTDCPSDLVP AFYSVGRTT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.522879
Match: 1l0qA
Description: Surface layer protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.66964148100475 bayes_pls_golite062009
protein binding 0.931624635835922 bayes_pls_golite062009
transporter activity 0.711149297585691 bayes_pls_golite062009
transmembrane transporter activity 0.517650155593165 bayes_pls_golite062009
substrate-specific transporter activity 0.276105437109391 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.113736784801445 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [416-625]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSKKSCFSER EWPISGGEWS PASCSYSEIV ITGHQDGSLK FWDSGAGTLQ ILYKLKTAKM  60
   61 FEKPRSHVAH SHPESDNPLA VHLIFLCSES RRLCVAGAMG QVMLFKFRKV ESTSEVLVLE 120
  121 IPILYENFDD IYGTSPECDF LTGHQVQKAE SSDSDKTAEC SLKVRNGAQR KPPGFQSQLV 180
  181 CLTTGPNRRN VQVTSLCISS SYGLMAYGTE 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.522879
Match: 1s4uX
Description: Crystal Structure analysis of the beta-propeller protein Ski8p
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [626-716]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YGLVIIDIIQ KICLLSVACP DLYGAHDPYS RTPKSPKRIE NKEEQSRSPS SDQVNKLDGT  60
   61 FSRSRSSSMS SIDMSSSESV TCLAFIESYA K

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [717-937]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RNDILTLVPT LWIGTSFGSI LTLFITMPER DVRKSQPVLI TINGGPVVRL KGSITSMSFL  60
   61 DSYGSIIPYT FETWRDEKRD NKDRTPTKSS SRTSPTFTPT TANTLSNTSV AGGASAGGGA 120
  121 GGGGGAGGGA ASGGAAAGGP AGGGAGAGSA AGAAGGVGSG VTSGGGMSSS SASSSGISGS 180
  181 VSTGLETLTD RQYIVIASEK QTKVFDVANQ CCINRIQLSE M

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.97
Match: 1wckA
Description: Crystal structure of the C-terminal domain of BclA, the major antigen of the exosporium of the Bacillus anthracis spore.
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [938-1097]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DFAVKAETIT MKDGSCLATY LSNGHLMVHS LPSLKLLLDT DFLPLMELSF QTKCKQGIVD  60
   61 PMLSIWGQQI IVHEDTTQIS KIFCFSHKGH GLYMASPTEI QKFTISSEFC QFILEMMGEL 120
  121 YTVHEMPEQP KEGFFKGLFG GGAKLLDREE LFGEQSGKPN 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [1098-1173]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RSVARHIPGP NLEQLGQRAS TAASEISRAH QLAMERGEKL NLLEERAERM ANTAQDFSGT  60
   61 AHQLMLKYKD KKWYQL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.09691
Match: 1urqA
Description: Crystal structure of neuronal Q-SNAREs in complex with R-SNARE motif of Tomosyn
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle