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View Structure Prediction Details

Protein: Sk1-PA, Sk1-PB
Organism: Drosophila melanogaster
Length: 641 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Sk1-PA, Sk1-PB.

Description E-value Query
Range
Subject
Range
gi|54643185, gi|... - gi|54643185|gb|EAL31929.1| GA14519-PA [Drosophila pseudoobscura], gi|125981739|ref|XP_001354873.1| G...
371.0 [0..22] [641..1]

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Predicted Domain #1
Region A:
Residues: [1-178]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTANTGTSGE NLMGNGGKTH EPSTPTSDTE VASGTPTELS EIFFVDNSRR KQSIKIQVKL  60
   61 CPEGVYLRRE TEEDDHINEQ LIRIDDIIGS RYGRRLKKRA RGGLNSCRNP NVPGQEADSE 120
  121 PDSDNSAYLY IYAYLKKEKP LRRVQTLRIL RFRSSNDYGV NLQTAEMWHH TIRKHKRG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.30103
Match: 1r79A
Description: Solution Structure of The C1 Domain of The Human Diacylglycerol Kinase Delta
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.01489434558857 bayes_pls_golite062009
protein binding 0.595458677481796 bayes_pls_golite062009
catalytic activity 0.564904183614451 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.509180585718177 bayes_pls_golite062009
kinase activity 0.502413328106933 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.416811228361087 bayes_pls_golite062009
transferase activity 0.255707908488426 bayes_pls_golite062009
protein kinase activity 0.197456871880971 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [179-512]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NGSSSPADCG KQLLILLNPK SGSGKGRELF QKQVAPLLTE AEVQYDLQIT THPQYAKEFV  60
   61 RTRRDLLTRY SGIVVASGDG LFYEVLNGLM ERMDWRRACR ELPLGIIPCG SGNGLAKSVA 120
  121 HHCNEPYEPK PILHATLTCM AGKSTPMDVV RVELATRDKH FVMYSFLSVG WGLIADIDIE 180
  181 SERLRSIGAQ RFTLWAIKRL IGLRSYKGRV SYLLGKGKKE PPVEAARELP AESTAAGIRS 240
  241 SLPLNAGEFH DLPEEEEGEA VLDGEQFADA ISLDRSVYRQ HADSWHSAMS RRTAYYSLGG 300
  301 PSMRSNRSRM SISQRIEAAN AEFAERVPTG TIPP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.69897
Match: 2jgrA
Description: No description for 2jgrA was found.

Predicted functions:

Term Confidence Notes
kinase activity 1.93010589087203 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.6993468998669 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.62136531467279 bayes_pls_golite062009
transferase activity 1.1287574677626 bayes_pls_golite062009
catalytic activity 0.704900964793432 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [513-641]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LQMPLLSSDG WICEDGDFVM VHAAYTTHLS SDVFFAPESR LDDGLIYLVI IRRGVSRHQL  60
   61 LNFMLNLNAG THLPIGEDPF IKVVPCRAFR IEPSSSDGIL VVDGERVEYG PIQAEVMPGL 120
  121 INVMTTSGQ

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.75
Match: 2bonA
Description: No description for 2bonA was found.

YRC Informatics Platform - Version 3.0
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