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View Structure Prediction Details

Protein: CG11284-PA, FBpp...
Organism: Drosophila melanogaster
Length: 250 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG11284-PA, FBpp....

Description E-value Query
Range
Subject
Range
CAH2_TRIHK - Carbonic anhydrase 2 OS=Tribolodon hakonensis GN=ca2 PE=2 SV=3
325.0 [0..2] [238..26]
gi|56554783 - gi|56554783|gb|AAV97962.1| carbonic anhydrase [Pseudopleuronectes americanus]
317.0 [0..2] [238..24]
CAHZ_DANRE - Carbonic anhydrase OS=Danio rerio GN=cahz PE=1 SV=2
316.0 [0..2] [238..26]
gi|22252956 - gi|22252956|gb|AAM94169.1| erythrocyte carbonic anhydrase [Lepisosteus osseus]
313.0 [0..2] [238..26]
gi|218931238, gi... - gi|61506858|dbj|BAD36835.2| carbonic anhydrase 1 [Oncorhynchus mykiss], dbj|BAD36836.1| carbonic anh...
312.0 [0..2] [238..26]
gi|37221537 - gi|37221537|gb|AAQ89896.1| carbonic anhydrase [Oreochromis mossambicus]
311.0 [0..3] [238..25]
gi|73762632 - gi|73762632|gb|AAZ83743.1| carbonic anhydrase [Cyprinus carpio]
307.0 [0..2] [238..26]

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Predicted Domain #1
Region A:
Residues: [1-250]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPVQSPIEIS NRAIEHIDDV DPLEYHGHWE PVGVARVQNT GTSAMVTFSK RKQQPYIIGG  60
   61 ALEQDMYVFE QLHFHWSDCD ESGCEHTLEG MKYSMEAHAV HYNSKYKDFT EAKNKPDGLA 120
  121 VVAFFIQACG EKDCPEFKKI TEGIRIVQKI HTSASLDSDC LSWIGLQELS KHYYTYKGSL 180
  181 TTAPYFESVT WIIYRTPIYV SRGQVQVFRN LQSCPKDESK KIVNNYREIQ RPHKDPEIFF 240
  241 ARNTNPKSKL 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 81.522879
Match: 1ugfA
Description: HUMAN CARBONIC ANHYDRASE II [HCAII] (E.C.4.2.1.1) MUTANT WITH ALA 65 REPLACED BY THR (A65T)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.59667704693142 bayes_pls_golite062009
protein binding 1.30419076438266 bayes_pls_golite062009
catalytic activity 0.97285738666961 bayes_pls_golite062009
transition metal ion binding 0.36067052386032 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle