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View Structure Prediction Details

Protein: Caf1-180-PB
Organism: Drosophila melanogaster
Length: 1183 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Caf1-180-PB.

Description E-value Query
Range
Subject
Range
gi|76643975 - gi|76643975|ref|XP_883032.1| PREDICTED: similar to Myosin-8 (Myosin heavy chain, skeletal muscle, pe...
340.0 [0..2] [1114..847]

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Predicted Domain #1
Region A:
Residues: [1-352]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHAGVVKTPL SGRKKDAAVP AKSAEKTASG GKKFVQTRLP FKLLTPGGGA VPTSSSSSSS  60
   61 PATIGSGPVT VILDEDDPAP RKRKLSYDDE SPSEGTGCST GQLRRSTSKE NLDLASSIAT 120
  121 KKVKTTDSVV EDVIELDEDE ADKEIEDQDQ LVEAKSSKEV KLKPKKSEGK KGSPAPIQIK 180
  181 LPLVNKRSKR RKSLKKSEEP LETSTADVAK GDSESSDDIE IIAEELNPQK RQKVQTPREK 240
  241 SPENSSTSGK HTEEVMQKNG KDSKKQEESM KAVKESKKEE PKTAEQNKKN DQATIDLFMG 300
  301 KKMETNKKDK PEVKTTAKDN KKDPLIAEDS KPKEVPKKET SKTGGKGKKE GA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.522879
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [353-632]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPAEKSKKEE KEDSTTKSKK EKADSPANNQ KEQQIGVKKK TSEPEDASNS HKSVTAKKDS  60
   61 KKDEASTQVK SDNESPEAAE ISMILSTSEA NSSSSEHEMD ADTDTAATDR PSAQKETRLN 120
  121 RKSLPEVTGA PKGLTPKQQR LMEQRKKARE EKEQKLAEER RLKQQDKEHR EQQKKQERDE 180
  181 KEQQRKLERD QKEQQRKMEK EEKERKRQAE VDSKNEEKRK RNEAKEEVQR KKDEERRKKE 240
  241 QEREEAEQKK KRAAESFSKF FVPKQPKCGS GSNNTSYLEH 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.03
Match: 2i1jA
Description: No description for 2i1jA was found.

Predicted Domain #3
Region A:
Residues: [633-798]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EQSSCDSSKA SSQTLAFRPF QIKDDMLLAP IVRNSLGQEQ RSQLDGLFRH RDEEADDEEE  60
   61 EEEQDIVRRK PPNRANLYLS ELSSGRRKPL KMQRDVKLQR RTKDEEDDDD VQVIDYLSPA 120
  121 GLPIEVEQPK QLTRMKAKYL HFADNRRPPY YGTWRKKSSS ISARRP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [799-1183]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LAQDKVLFDY EVDSDCEWEE EEPGESLSAS EDEKEKESEE ESEEEYNEWY VPHGHLSDEE  60
   61 LQNDGDGMED GHTREAQKAK LQVLQQEFAQ EMKKQTKKIK ARLLGPVWLD ENGNKSELFP 120
  121 AIFAHTIDMY ACWQVEPLSL EPPPEPERQD QTPEQPVPLQ LDDRLMQQLV RLTHGNRNSK 180
  181 TFLINEYLEY LKTQATAEAN QTTLPSKAVL REKFDELASW KTVELSTPEA AAASANSAKK 240
  241 GRKPKKRLCW VVASDMLEKF QLPDLQLQNQ WNYTLTPKVS DGPDAAQQEQ SPPADAVPAA 300
  301 SPASNQTTNS APTTPISGQT QAGQGVKKRA TLIMSVPRDQ PIPSATKNKL ISQFLQRQSD 360
  361 ASKPKEKMQE KPPPIVFDDV VMLSD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.0
Match: 1c1gA
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle