






| Protein: | Dok-PA |
| Organism: | Drosophila melanogaster |
| Length: | 622 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Dok-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
258.0 | [0..1] | [566..1] |
|
Region A: Residues: [1-238] |
1 11 21 31 41 51
| | | | | |
1 MDVEIPVLAG YLNVPTQTGF SLNRISKKKA CSRYCLLFKA SRHGIARLEM CESKEDRNPK 60
61 IFTLENCVKI TQEPPPERLI HIVKRQATLT LSTSSEEELK DWITALQTVA FCDTSPSGGI 120
121 GAIEEDNDLY CSSFDGLFII TLIPSEASIR CCIEPKTYML QMTPTELQLK SEDLGATIAM 180
181 WPYRFIRKYG YRDGKFTFEA GRKCTTGEGV FTLDHTNPQE VFRCMSAKMK SMKKLISG
|
| Detection Method: | |
| Confidence: | 60.522879 |
| Match: | 1qqgA |
| Description: | Insulin receptor substrate 1, IRS-1 |
Matching Structure (courtesy of the PDB):![]() |
|
| Term | Confidence | Notes |
| binding | 2.65091781683225 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 2.36862097678996 | bayes_pls_golite062009 |
| actin binding | 2.33076715684475 | bayes_pls_golite062009 |
| protein binding | 2.12168271674167 | bayes_pls_golite062009 |
| actin filament binding | 1.07760654703512 | bayes_pls_golite062009 |
| GTPase regulator activity | 0.355387992614734 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 0.335498703113274 | bayes_pls_golite062009 |
| enzyme regulator activity | 0.189879136353541 | bayes_pls_golite062009 |
|
Region A: Residues: [239-337] |
1 11 21 31 41 51
| | | | | |
1 DSLSTLECGE NQFSAAAGME PGSRSPLPPS PSSNPHGGEF EINSTQSCIS LRGFISSNDS 60
61 LNNFSAGGGG ASGATATGGG VLGSTGGITL SVPANSNSN
|
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [338-531] |
1 11 21 31 41 51
| | | | | |
1 SSSSKHIPNK PPRKSPTTHC DKYRNIVKYE PVAITTISSP SANSDVNSSV ILKPLEGESI 60
61 SLPETAADLP PDLPLRNESA SKAPPPERDY ECIENITEAW RTRGVGDVRH SERMPILCDT 120
121 SEFVRQRSVS KSTCGSQNTP KIIDIDIGEG CTSATSISES NYDRLDFLSP NNKTSSGYKT 180
181 IVNVTPGNRI RCSP
|
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [532-622] |
1 11 21 31 41 51
| | | | | |
1 PPPNEYELIA SPDTESFRKA DDSHRGYGVL RKASTTTNNN NLGISNSNIS GGSSTITTAT 60
61 ANKGGNLEAA AIDHRSYNGL NYTMVSKPKR V
|
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.