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View Structure Prediction Details

Protein: l(1)G0255-PB
Organism: Drosophila melanogaster
Length: 467 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for l(1)G0255-PB.

Description E-value Query
Range
Subject
Range
gi|50736122, gi|... - gi|57530433|ref|NP_001006382.1| fumarate hydratase [Gallus gallus], gi|53130266|emb|CAG31462.1| hypo...
559.0 [0..1] [467..41]

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Predicted Domain #1
Region A:
Residues: [1-467]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASQEFRVES DTFGELKVPA DKYYGAQTMR SQINFPIGGA TERMPKPVVQ AMGILKKAAA  60
   61 EVNKEFGLDS KVSEAISKAA DDVISGKLYD DHFPLVIWQT GSGTQSNMNV NEVISNRAIE 120
  121 LLGGKLGSKT PVHPNDHVNK SQSSNDTFPT AIHISVALEL NNNLKPAIKT LHDALRAKSE 180
  181 EFKDIIKIGR THTMDAVPLT LGQEFSGYAQ QLAYAQERID ACLPRVYELA LGGTAVGTGL 240
  241 NTRKGFAEKC AAKIAELTSL PFVTAPNKFE ALAARDAMVE VHGVLNTIAV SLMKIANDIR 300
  301 FLGSGPRCGL GELSLPENEP GSSIMPGKVN PTQCESLTML SAQVMGNQVA VTIGGSNGHF 360
  361 ELNVFKPLIV SNVLRSIRLL SDGSRTFTAN CVNGIQANRE NIAKIMNESL MLVTALNPHI 420
  421 GYDKAAKIAK TAHKNGTTLK EEAINLGYLT EQQFNDWVRP EQMLGPK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 155.0
Match: 1yfmA
Description: RECOMBINANT YEAST FUMARASE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
fumarate hydratase activity 4.22589182982073 bayes_pls_golite062009
catalytic activity 2.51282259572665 bayes_pls_golite062009
lyase activity 2.31268471569846 bayes_pls_golite062009
carbon-nitrogen lyase activity 2.2046475419807 bayes_pls_golite062009
histidine ammonia-lyase activity 0.948129236753279 bayes_pls_golite062009
amidine-lyase activity 0.901614580251298 bayes_pls_golite062009
binding 0.854855116369286 bayes_pls_golite062009
argininosuccinate lyase activity 0.617974375213548 bayes_pls_golite062009
ammonia-lyase activity 0.491229595527877 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle